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Q7W3V3 (AROE_BORPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Shikimate dehydrogenase
EC=1.1.1.25
Gene names
Name:aroE
Ordered Locus Names:BPP3924
OrganismBordetella parapertussis [Complete proteome] [HAMAP]
Taxonomic identifier519 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222

Sequence similarities

Belongs to the shikimate dehydrogenase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   LigandNADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionNADP binding

Inferred from electronic annotation. Source: InterPro

shikimate 3-dehydrogenase (NADP+) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 287287Shikimate dehydrogenase HAMAP MF_00222
PRO_0000325107

Regions

Nucleotide binding132 – 1365NADP By similarity

Sites

Active site711Proton acceptor Potential

Sequences

Sequence LengthMass (Da)Tools
Q7W3V3 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 8AB6BFEAD3882AB4

FASTA28729,606
        10         20         30         40         50         60 
MTLPASPPRY AVIGNPIAHS RSPQIHAMFS AQTGRPLRYE RLLAPVDGFL PTVQAFRESG 

        70         80         90        100        110        120 
GLGLNVTVPF KLEAYALAEA RLSERARLAG AVNTLSWRDG AWHGCNTDGV GLVNDLLRLG 

       130        140        150        160        170        180 
VALAGARVLL VGAGGAARGV LQPLAAAGCA RIHIVNRTAA RAAELAAAWR AAAPRTGTQV 

       190        200        210        220        230        240 
SAGALAQAAE PGGWDVAINA TASSLQDAAP DLPGGLYAPD ALAYDMMYGA RPTAFMRQAE 

       250        260        270        280 
ADGAARCADG LGMLVGQAAE SFHIWHGVRP DPGPVLLALR TELLAAG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX640435 Genomic DNA. Translation: CAE39207.1.
RefSeqNP_886074.1. NC_002928.3.

3D structure databases

HSSPHSSP built from PDB template 1NYT based on UniProtKB P15770.
ProteinModelPortalQ7W3V3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1666328.
GenomeReviewsGene locus BPP3924 in contig BX470249_GR.
KEGGbpa:BPP3924.
NMPDRfig|257311.1.peg.3708.
PATRIC21151922. VBIBorPar43418_4119.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG553408.
OMANTLWIEE.
PhylomeDBQ7W3V3.
ProtClustDBPRK00258.

Enzyme and pathway databases

BioCycBPAR257311:BPP3924-MONOMER.

Family and domain databases

HAMAPMF_00222. Shikimate_DH_AroE.
[Tree]
InterProIPR016040. NAD(P)-bd_dom.
IPR011342. Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00014.
PfamPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00507. AroE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROE_BORPA
AccessionPrimary (citable) accession number: Q7W3V3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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