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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:BPP3927
OrganismiBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Taxonomic identifieri257311 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
Proteomesi
  • UP000001421 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001979791 – 277Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST277

Structurei

3D structure databases

ProteinModelPortaliQ7W3V0
SMRiQ7W3V0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q7W3V0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGSIWTIGD VQGCCAPLAE LLAHPEIAGD TDSRFWFAGD LVNRGPQSLA
60 70 80 90 100
VLRRIMAMGE RCTAVLGNHD LHLLAAYAGV RKPSKSDTLD EVLQAPDAVD
110 120 130 140 150
LIDWLRFRPL AHYEAGHLMV HAGVLAKWDV AKTLALAGEV EQALRGPNWR
160 170 180 190 200
KALQKMYGNE PATWKDDHTG GKRMRVIINA LTRIRLCTPS GHMEFATKVA
210 220 230 240 250
PGAWPAGLVP WFDVPNRATR DVTVVFGHWS TLGLLMRPDV ICLDTGCVWG
260 270
GALSALRLHD RKLVQVKCKR FQDPNGD
Length:277
Mass (Da):30,511
Last modified:October 1, 2003 - v1
Checksum:iDE27E34DEC3404E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640435 Genomic DNA Translation: CAE39210.1
RefSeqiWP_003814962.1, NC_002928.3

Genome annotation databases

EnsemblBacteriaiCAE39210; CAE39210; BPP3927
KEGGibpa:BPP3927

Similar proteinsi

Entry informationi

Entry nameiAPAH_BORPA
AccessioniPrimary (citable) accession number: Q7W3V0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health