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Q7W3V0

- APAH_BORPA

UniProt

Q7W3V0 - APAH_BORPA

Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Functioni

    Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

    Catalytic activityi

    P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

    GO - Molecular functioni

    1. bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciBPAR257311:BPP3927-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
    Alternative name(s):
    Ap4A hydrolaseUniRule annotation
    Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
    Diadenosine tetraphosphataseUniRule annotation
    Gene namesi
    Name:apaHUniRule annotation
    Ordered Locus Names:BPP3927
    OrganismiBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
    Taxonomic identifieri257311 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
    ProteomesiUP000001421: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 277277Bis(5'-nucleosyl)-tetraphosphatase, symmetricalPRO_0000197979Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi257311.BPP3927.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7W3V0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Ap4A hydrolase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0639.
    HOGENOMiHOG000251871.
    KOiK01525.
    OMAiINAFTRM.
    OrthoDBiEOG66B3WP.

    Family and domain databases

    Gene3Di3.60.21.10. 2 hits.
    HAMAPiMF_00199. ApaH.
    InterProiIPR004617. ApaH.
    IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
    SUPFAMiSSF56300. SSF56300. 1 hit.
    TIGRFAMsiTIGR00668. apaH. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7W3V0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKGSIWTIGD VQGCCAPLAE LLAHPEIAGD TDSRFWFAGD LVNRGPQSLA    50
    VLRRIMAMGE RCTAVLGNHD LHLLAAYAGV RKPSKSDTLD EVLQAPDAVD 100
    LIDWLRFRPL AHYEAGHLMV HAGVLAKWDV AKTLALAGEV EQALRGPNWR 150
    KALQKMYGNE PATWKDDHTG GKRMRVIINA LTRIRLCTPS GHMEFATKVA 200
    PGAWPAGLVP WFDVPNRATR DVTVVFGHWS TLGLLMRPDV ICLDTGCVWG 250
    GALSALRLHD RKLVQVKCKR FQDPNGD 277
    Length:277
    Mass (Da):30,511
    Last modified:October 1, 2003 - v1
    Checksum:iDE27E34DEC3404E9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX640435 Genomic DNA. Translation: CAE39210.1.
    RefSeqiNP_886077.1. NC_002928.3.

    Genome annotation databases

    EnsemblBacteriaiCAE39210; CAE39210; BPP3927.
    GeneIDi1666331.
    KEGGibpa:BPP3927.
    PATRICi21151928. VBIBorPar43418_4122.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX640435 Genomic DNA. Translation: CAE39210.1 .
    RefSeqi NP_886077.1. NC_002928.3.

    3D structure databases

    ProteinModelPortali Q7W3V0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257311.BPP3927.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE39210 ; CAE39210 ; BPP3927 .
    GeneIDi 1666331.
    KEGGi bpa:BPP3927.
    PATRICi 21151928. VBIBorPar43418_4122.

    Phylogenomic databases

    eggNOGi COG0639.
    HOGENOMi HOG000251871.
    KOi K01525.
    OMAi INAFTRM.
    OrthoDBi EOG66B3WP.

    Enzyme and pathway databases

    BioCyci BPAR257311:BPP3927-MONOMER.

    Family and domain databases

    Gene3Di 3.60.21.10. 2 hits.
    HAMAPi MF_00199. ApaH.
    InterProi IPR004617. ApaH.
    IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000903. B5n-ttraPtase_sm. 1 hit.
    SUPFAMi SSF56300. SSF56300. 1 hit.
    TIGRFAMsi TIGR00668. apaH. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica."
      Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S.
      , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.
      Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 12822 / ATCC BAA-587 / NCTC 13253.

    Entry informationi

    Entry nameiAPAH_BORPA
    AccessioniPrimary (citable) accession number: Q7W3V0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2005
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3