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Q7W3V0 (APAH_BORPA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

EC=3.6.1.41
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene names
Name:apaH
Ordered Locus Names:BPP3927
OrganismBordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) [Complete proteome] [HAMAP]
Taxonomic identifier257311 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity. HAMAP-Rule MF_00199

Catalytic activity

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP. HAMAP-Rule MF_00199

Sequence similarities

Belongs to the Ap4A hydrolase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionbis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 277277Bis(5'-nucleosyl)-tetraphosphatase, symmetrical HAMAP-Rule MF_00199
PRO_0000197979

Sequences

Sequence LengthMass (Da)Tools
Q7W3V0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: DE27E34DEC3404E9

FASTA27730,511
        10         20         30         40         50         60 
MKGSIWTIGD VQGCCAPLAE LLAHPEIAGD TDSRFWFAGD LVNRGPQSLA VLRRIMAMGE 

        70         80         90        100        110        120 
RCTAVLGNHD LHLLAAYAGV RKPSKSDTLD EVLQAPDAVD LIDWLRFRPL AHYEAGHLMV 

       130        140        150        160        170        180 
HAGVLAKWDV AKTLALAGEV EQALRGPNWR KALQKMYGNE PATWKDDHTG GKRMRVIINA 

       190        200        210        220        230        240 
LTRIRLCTPS GHMEFATKVA PGAWPAGLVP WFDVPNRATR DVTVVFGHWS TLGLLMRPDV 

       250        260        270 
ICLDTGCVWG GALSALRLHD RKLVQVKCKR FQDPNGD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640435 Genomic DNA. Translation: CAE39210.1.
RefSeqNP_886077.1. NC_002928.3.

3D structure databases

ProteinModelPortalQ7W3V0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257311.BPP3927.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE39210; CAE39210; BPP3927.
GeneID1666331.
KEGGbpa:BPP3927.
PATRIC21151928. VBIBorPar43418_4122.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000251871.
KOK01525.
OMAWLRHQPL.
OrthoDBEOG66B3WP.
ProtClustDBPRK00166.

Enzyme and pathway databases

BioCycBPAR257311:BPP3927-MONOMER.

Family and domain databases

HAMAPMF_00199. ApaH.
InterProIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF000903. B5n-ttraPtase_sm. 1 hit.
TIGRFAMsTIGR00668. apaH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPAH_BORPA
AccessionPrimary (citable) accession number: Q7W3V0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 1, 2003
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families