Reviewed, UniProtKB/Swiss-Prot Q7W2Q2 (SYR_BORPA)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BPP4352

Organism

Bordetella parapertussis [Complete proteome] [HAMAP]

Taxonomic identifier

519 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	561 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 561	561	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000151535
Regions
	Motif	129 – 139	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q7W2Q2-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: FC5EF3A4C6984E13	FASTA	561	61,547
	10 20 30 40 50 60 MLLEQQKQLI SLIQAAVAQC LPEAQAQVQL ERPKVAAHGD IATNVAMQLA KPARRNPREL 70 80 90 100 110 120 AQGIVDALMA QPQARELIQD AEIAGPGFIN FRLTPAARQA VVQAVASQAD AYGRAPRNGE 130 140 150 160 170 180 KVLVEFVSAN PTGPLHVGHA RQAALGDAIC RLYDASGWDV TREFYYNDAG NQIDNLAISV 190 200 210 220 230 240 QARGRGIAPD APDYPTDGYK GDYIVEIARD FAARKSVQAS DGQPVTATGD LDSLDDIRAF 250 260 270 280 290 300 AVAYLRREQD LDLQAFGLAF DNYFLESSLY ASGRVQETVD TLVAKGHTYE EGGALWLRTT 310 320 330 340 350 360 ELGTGDDKDR VMRKSEGGYT YFVPDVAYHK VKWERGFHHA VNIQGSDHHG TVARVRAGLQ 370 380 390 400 410 420 GLEAGIPKDF PAYVLHKMVK VMRGGEEVKI SKRAGSYVTM RDLIDWVGRD AVRYFLIQRR 430 440 450 460 470 480 ADTEFVFDID LALSKSDENP VYYIQYAHAR ICTMIGNSGA SAAEIAQADT ALLTAPSEYA 490 500 510 520 530 540 LLQRLAEFPQ VVALAAQELA PHHVAFWLRD CASDFHAWYN AERVLVDEPA LKLARLRLAA 550 560 TTRQVLANGL ALLGVSAPDR M

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed: 12910271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12822 / ATCC BAA-587 / NCTC 13253.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX640436 Genomic DNA. Translation: CAE39631.1.
RefSeq	NP_886480.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1665559.
KEGG	bpa:BPP4352.
NMPDR	fig|257311.1.peg.4114.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG695395.
OMA	LGDCIAN.
Enzyme and pathway databases
BioCyc	BPAR257311:BPP4352-MONOMER.
BRENDA	6.1.1.19. 263123.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM00836. DALR_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BORPA

Accession

Primary (citable) accession number: Q7W2Q2

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	October 1, 2003
Last modified:	February 9, 2010
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)