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Q7W0K0 (SYR_BORPE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BP0115
OrganismBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) [Reference proteome] [HAMAP]
Taxonomic identifier257313 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length560 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Sequence caution

The sequence CAE40495.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 560560Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151536

Regions

Motif164 – 17411"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q7W0K0 [UniParc].

Last modified December 15, 2003. Version 2.
Checksum: FF6C5F443BB1EB2E

FASTA56061,387
        10         20         30         40         50         60 
MLLEQQKQLI SLIQAAVAQC LPEAQAQVQL ERPKVAAHGD IATNVAMQLA KPARRNPREL 

        70         80         90        100        110        120 
AQGIVDALMA QPQARELIQD AEIAGPGFIN FRLTPAARQA VVQAVASQAD AYGRAPRNGE 

       130        140        150        160        170        180 
KVLVEFVSAN PTGPLHVGHA RQAALGDAIC RLYDASGWDV TREFYYNDAG NQIDNLAISV 

       190        200        210        220        230        240 
QARGRGIAPD APDYPADGYK GDYIVEIARD FAARKSVQAS DGQPVTATGD LDSLDDIRAF 

       250        260        270        280        290        300 
AVAYLRREQD LDLQAFGLAF DNYFLESSLY ASGRVQETVD TLVAKGHTYE EGGALWLRTT 

       310        320        330        340        350        360 
ELGTGDDKDR VMRKSEGGYT YFVPDVAYHK VKWERGFHHA VNIQGSDHHG TVARVRAGLQ 

       370        380        390        400        410        420 
GLAGIPKDFP AYVLHKMVKV MRGGEEVKIS KRAGSYVTMR DLIDWVGRDA VRYFLIQRRA 

       430        440        450        460        470        480 
DTEFVFDIDL ALSKSDENPV YYIQYAHARI CTMIGNSGAS AAEIAQADTA LLTAPSEYAL 

       490        500        510        520        530        540 
LQRLAEFPQV VALAAQELAP HHVAFWLRDC ASDFHAWYNA ERVLVDEPAL KLARLRLAAT 

       550        560 
TRQVLANGLA LLGVSAPDRM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640411 Genomic DNA. Translation: CAE40495.1. Different initiation.
RefSeqNP_879017.1. NC_002929.2.

3D structure databases

ProteinModelPortalQ7W0K0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257313.BP0115.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE40495; CAE40495; BP0115.
GeneID2667420.
KEGGbpe:BP0115.
PATRIC21153220. VBIBorPer7866_0117.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycBPER257313:BP0115-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BORPE
AccessionPrimary (citable) accession number: Q7W0K0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: April 16, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries