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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei182 – 1821UniRule annotation
Active sitei625 – 6251UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciBPER257313:BP0215-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:BP0215
OrganismiBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Taxonomic identifieri257313 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
ProteomesiUP000002676 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 980980Phosphoenolpyruvate carboxylasePRO_0000166582Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257313.BP0215.

Structurei

3D structure databases

ProteinModelPortaliQ7W0D0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7W0D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYNAPVSN CQFRLTHILP IPQRHGAPTD PFQMNAIRQQ SDSAEPLRHD
60 70 80 90 100
IRLLGRCLGE VIQACEGKRV YDTIETLRRT AVRFRRAGDP ADDKLLQARV
110 120 130 140 150
KQLRGNDPNS VARAFSYFLH LSNIAEDRDQ NRRQRERALA GAGPERGSLR
160 170 180 190 200
QAIESLKAQG VNNARIRRLL SEACVMPVLT AHPTEVQRKS TLDVHREISS
210 220 230 240 250
LLVQRERELT ADELSELDLA LIGQVATLWQ TRMLRYTRLT VADEIENALS
260 270 280 290 300
YYRSTFLNVI PRVYGDLARL LNREPVKPFT PPPPPLEPFL RMGSWIGGDR
310 320 330 340 350
DGNPNVDAAT LERALLRQAT VLFEHYLQEV HALGAELSAS TLLIEADPAL
360 370 380 390 400
LALADAGGDD SPHRRDEPYR RALIGIYARL AATARHLTGQ KLARRATVPA
410 420 430 440 450
APYDTPDALA ADLAVIAASL SARHGAPIAR LRLSGLQQAV TVFGFHLATV
460 470 480 490 500
DLRQSSDVHE RVLAELFARA GDGIDGQAVD YLALDEAARV AGRELAHARP
510 520 530 540 550
LASPWIAYSE ETASELAVLR AAAAGRARYG RQAVLQSIVS HTETLSDLLE
560 570 580 590 600
VLVLQKEAGL IAPPGETIAP GDGLMVVPLF ETIPDLQRGP EIMAAWLDLP
610 620 630 640 650
EVRQRVRLAQ GDTQEVMLGY SDSNKDGGFL TSNWSLYQAE RALVDVFSAR
660 670 680 690 700
SVRLRMFHGR GDSVGRGGGS SYDAILAQPP GTVAGQLRLT EQGEVIQSKY
710 720 730 740 750
KDAEVGRWHL ELLVAATLES SLAPQAAATS AEDAHMQQHA PAMSFMSELA
760 770 780 790 800
QRTYRGLVYD TPGFADYFFA ATPISEIAGL NIGSRPASRK KGQHIEDLRA
810 820 830 840 850
IPWGFSWAQC RLMLTGWYGM GSAIEAYLET GAQGAPRSRR ARLAQLREMA
860 870 880 890 900
SDWPAFRTLL SNMEMVLAKS DLAIAAGYAQ LVPRRGLRER VFGAITAEHG
910 920 930 940 950
RTLAMLRLLT RRDLLADNPG LMASLRERFA YIDPLNYLQI ELIKRHRAAQ
960 970 980
RRAGDDADIR VPRAIHLTIN GIAAGLRNSG
Length:980
Mass (Da):107,774
Last modified:October 1, 2003 - v1
Checksum:iE586FA1524F8F745
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640411 Genomic DNA. Translation: CAE40595.1.
RefSeqiNP_879103.1. NC_002929.2.
WP_010929690.1. NC_002929.2.

Genome annotation databases

EnsemblBacteriaiCAE40595; CAE40595; BP0215.
GeneIDi2664728.
KEGGibpe:BP0215.
PATRICi21153450. VBIBorPer7866_0232.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640411 Genomic DNA. Translation: CAE40595.1.
RefSeqiNP_879103.1. NC_002929.2.
WP_010929690.1. NC_002929.2.

3D structure databases

ProteinModelPortaliQ7W0D0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi257313.BP0215.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE40595; CAE40595; BP0215.
GeneIDi2664728.
KEGGibpe:BP0215.
PATRICi21153450. VBIBorPer7866_0232.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBPER257313:BP0215-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica."
    Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S.
    , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.
    Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tohama I / ATCC BAA-589 / NCTC 13251.

Entry informationi

Entry nameiCAPP_BORPE
AccessioniPrimary (citable) accession number: Q7W0D0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2003
Last modified: May 27, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.