Q7VZG1 (KCY_BORPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	BP0949

Organism

Bordetella pertussis

Taxonomic identifier

520 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Cytidylate kinase HAMAP MF_00238		PRO_0000131889
Regions
	Nucleotide binding	17 – 25	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7VZG1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: BAF1E2E2FA5EFD0A	FASTA	223	23,903
	10 20 30 40 50 60 MAIFASAGAA PVITIDGPTA SGKGTIAHRV AKQLGWDVLD SGALYRLTAL AALRRGLPAT 70 80 90 100 110 120 DEPAVAAVAQ ALDVRFDGPH VYLEGRDAGH EIRQEEVGNY ASRIAAYPGV RQALLERQRA 130 140 150 160 170 180 FRQPPGLVAD GRDMGAVVFP DASLKIFLVA DVEARAQRRC KQLIEKGISA NLDDLLRDMR 190 200 210 220 ERDARDTQRA VAPLAPAADA HVLDSSGLTI EQTVQAVLDF WCA

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed: 12910271] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tohama I / ATCC BAA-589 / NCTC 13251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX640413 Genomic DNA. Translation: CAE41251.1.
RefSeq	NP_879750.1. NC_002929.2.
3D structure databases
ProteinModelPortal	Q7VZG1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2664293.
GenomeReviews	Gene locus BP0949 in contig BX470248_GR.
KEGG	bpe:BP0949.
NMPDR	fig|257313.1.peg.829.
PATRIC	21155020. VBIBorPer7866_1013.
Phylogenomic databases
HOGENOM	HBG354377.
OMA	DIGTVIC.
PhylomeDB	Q7VZG1.
ProtClustDB	PRK00023.
Enzyme and pathway databases
BioCyc	BPER257313:BP0949-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BORPE

Accession

Primary (citable) accession number: Q7VZG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program