Q7VYT6 (Q7VYT6_BORPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alanine racemase, catabolic EMBL CAE41517.1
EC=5.1.1.1 EMBL CAE41517.1

Gene names

Name:	dadX EMBL CAE41517.1
Ordered Locus Names:	BP1221

Organism

Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) [Reference proteome] [HAMAP]

Taxonomic identifier

257313 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella › Bordetella pertussis

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL CAE41517.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7VYT6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: E8E1D6337D60222F	FASTA	375	39,532
	10 20 30 40 50 60 MPRPIFASIS QSALRHNLAT VRRHLDDVAA KADGTPPSIW AVIKANAYGH GIEQAVAGFS 70 80 90 100 110 120 AAQGLAMLDL QEAVRCREAG WGGPILLLEG FFQPSDLEIV DRYHLATTVH TREQFDMLAH 130 140 150 160 170 180 ARLSRRVDIM VKLNSGMNRL GFAPDAYGSA YARAQQLHEY GVVGGIGKMT HFACADGPQG 190 200 210 220 230 240 VTQQMNVFNG ATAHLAGATS VCNSAATLRY ADLAVGHDGQ THWVRPGICL YGASPFADAQ 250 260 270 280 290 300 AGAFGLIPAM TLRSELIAIQ DIPAGAAVGY GAIFRADRPM RIGVVACGYA DGYPRHAGTG 310 320 330 340 350 360 TPLTVGGVRT RLVGRVSMDM LMVDLDPVPA AGIGTPVVLW GEDGPSVDEV AEAAGTIGYE 370 LLCALAPRVP VRHEG

References

[1]

"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tohama I / ATCC BAA-589 / NCTC 13251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX640414 Genomic DNA. Translation: CAE41517.1.
RefSeq	NP_879994.1. NC_002929.2.
3D structure databases
HSSP	HSSP built from PDB template 1NIU based on UniProtKB P10724.
ProteinModelPortal	Q7VYT6.
ModBase	Search...
Protein-protein interaction databases
STRING	257313.BP1221.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAE41517; CAE41517; BP1221.
GeneID	2665336.
KEGG	bpe:BP1221.
PATRIC	21155632. VBIBorPer7866_1315.
Phylogenomic databases
HOGENOM	HOG000031446.
KO	K01775.
OMA	SVELWGD.
ProtClustDB	CLSK920285.
Enzyme and pathway databases
BioCyc	BPER257313:BP1221-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7VYT6_BORPE

Accession

Primary (citable) accession number: Q7VYT6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)