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Q7VYB8 (Q7VYB8_BORPE) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387 EMBL CAE41721.1
Ordered Locus Names:BP1431
OrganismBordetella pertussis
Taxonomic identifier520 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
Q7VYB8 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 4F9A7C2FC0242B56

FASTA26427,924
        10         20         30         40         50         60 
MSGNIHPTAV VDPAAQIDSS VVIGPYSVVG PGVSIAAGTE VGAHCVLDGV TSIGRDNRFY 

        70         80         90        100        110        120 
RFCSIGGMPQ DKKYSGEPTR LVIGDRNTVR EFTTFNTGTV QDGGVTSIGD DNWIMAYVHI 

       130        140        150        160        170        180 
AHDCHIGNNT ILANSVQLGG HVQVGDWAIV GGLTGVHQFA KIGAHSMTGG NSSLMQDAPP 

       190        200        210        220        230        240 
FVLAAGNPCR PVGVNVEGLK RRGFSAAAIS ALRDAYKSIY RRGLSLDEGR AELRARQQAE 

       250        260 
PDVAEHLQTM LDFLDASTRG IIRP

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX640415 Genomic DNA. Translation: CAE41721.1.
RefSeqNP_880173.1. NC_002929.2.

3D structure databases

HSSPHSSP built from PDB template 1J2Z based on UniProtKB O25927.
ProteinModelPortalQ7VYB8.
SMRQ7VYB8. Positions 2-263.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2665349.
GenomeReviewsGene locus BP1431 in contig BX470248_GR.
KEGGbpe:BP1431.
NMPDRfig|257313.1.peg.1251.
PATRIC21156076. VBIBorPer7866_1534.

Phylogenomic databases

HOGENOMHBG659295.
OMAREFCTFN.
PhylomeDBQ7VYB8.
ProtClustDBPRK05289.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 2 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ7VYB8_BORPE
AccessionPrimary (citable) accession number: Q7VYB8
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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