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Q7VVZ2 (Q7VVZ2_BORPE) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CAE42760.1
Ordered Locus Names:BP2488 EMBL CAE42760.1
OrganismBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) [Reference proteome] [HAMAP]
Taxonomic identifier257313 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Sequences

Sequence LengthMass (Da)Tools
Q7VVZ2 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 426D99B735096907

FASTA41845,794
        10         20         30         40         50         60 
MSYQHIKVPT GGQKITVNAD YSLNVPDQVI IPVIEGDGTG ADITPVMIKV VDAAVQKAYA 

        70         80         90        100        110        120 
GKRKIHWMEV YAGEKATKVY GPDVWLPEET LDAVKDYVVS IKGPLTTPVG GGIRSLNVAL 

       130        140        150        160        170        180 
RQQLDLYVCL RPVRYFKGVP SPVREPEKTD MVIFRENSED IYAGIEYMAE SEQAKDLIQY 

       190        200        210        220        230        240 
LQTKLGVTKI RFPNTSSIGI KPVSREGTER LVRKALQYAI DNDRASVTLV HKGNIMKFTE 

       250        260        270        280        290        300 
GGFRDWGYAL AQNEFGAQPI DGGPWCKFKN PKTGREIIVK DSIADAFLQQ ILLRPAEYDV 

       310        320        330        340        350        360 
IATLNLNGDY ISDALAAQVG GIGIAPGANL SDSVAMFEAT HGTAPKYAGK DYVNPGSEIL 

       370        380        390        400        410 
SAEMMLRHMG WTEAADLIIA SMEKSILSKK VTYDFARLLE GATQVSCSGF GQVMIDNM 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640418 Genomic DNA. Translation: CAE42760.1.
RefSeqNP_881115.1. NC_002929.2.

3D structure databases

ProteinModelPortalQ7VVZ2.
SMRQ7VVZ2. Positions 6-418.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257313.BP2488.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE42760; CAE42760; BP2488.
GeneID2666686.
KEGGbpe:BP2488.
PATRIC21158406. VBIBorPer7866_2684.

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
OrthoDBEOG6SNDTP.
ProtClustDBPRK07006.

Enzyme and pathway databases

BioCycBPER257313:BP2488-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7VVZ2_BORPE
AccessionPrimary (citable) accession number: Q7VVZ2
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: November 13, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)