Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7VVZ2

- Q7VVZ2_BORPE

UniProt

Q7VVZ2 - Q7VVZ2_BORPE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciBPER257313:BP2488-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:BP2488Imported
OrganismiBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)Imported
Taxonomic identifieri257313 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella
ProteomesiUP000002676: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi257313.BP2488.

Structurei

3D structure databases

ProteinModelPortaliQ7VVZ2.
SMRiQ7VVZ2. Positions 6-418.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000021113.
KOiK00031.
OMAiRYAIDND.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7VVZ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYQHIKVPT GGQKITVNAD YSLNVPDQVI IPVIEGDGTG ADITPVMIKV
60 70 80 90 100
VDAAVQKAYA GKRKIHWMEV YAGEKATKVY GPDVWLPEET LDAVKDYVVS
110 120 130 140 150
IKGPLTTPVG GGIRSLNVAL RQQLDLYVCL RPVRYFKGVP SPVREPEKTD
160 170 180 190 200
MVIFRENSED IYAGIEYMAE SEQAKDLIQY LQTKLGVTKI RFPNTSSIGI
210 220 230 240 250
KPVSREGTER LVRKALQYAI DNDRASVTLV HKGNIMKFTE GGFRDWGYAL
260 270 280 290 300
AQNEFGAQPI DGGPWCKFKN PKTGREIIVK DSIADAFLQQ ILLRPAEYDV
310 320 330 340 350
IATLNLNGDY ISDALAAQVG GIGIAPGANL SDSVAMFEAT HGTAPKYAGK
360 370 380 390 400
DYVNPGSEIL SAEMMLRHMG WTEAADLIIA SMEKSILSKK VTYDFARLLE
410
GATQVSCSGF GQVMIDNM
Length:418
Mass (Da):45,794
Last modified:October 1, 2003 - v1
Checksum:i426D99B735096907
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640418 Genomic DNA. Translation: CAE42760.1.
RefSeqiNP_881115.1. NC_002929.2.

Genome annotation databases

EnsemblBacteriaiCAE42760; CAE42760; BP2488.
GeneIDi2666686.
KEGGibpe:BP2488.
PATRICi21158406. VBIBorPer7866_2684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640418 Genomic DNA. Translation: CAE42760.1 .
RefSeqi NP_881115.1. NC_002929.2.

3D structure databases

ProteinModelPortali Q7VVZ2.
SMRi Q7VVZ2. Positions 6-418.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257313.BP2488.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE42760 ; CAE42760 ; BP2488 .
GeneIDi 2666686.
KEGGi bpe:BP2488.
PATRICi 21158406. VBIBorPer7866_2684.

Phylogenomic databases

HOGENOMi HOG000021113.
KOi K00031.
OMAi RYAIDND.
OrthoDBi EOG6SNDTP.

Enzyme and pathway databases

BioCyci BPER257313:BP2488-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica."
    Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S.
    , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.
    Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tohama I / ATCC BAA-589 / NCTC 13251Imported.

Entry informationi

Entry nameiQ7VVZ2_BORPE
AccessioniPrimary (citable) accession number: Q7VVZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: November 26, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3