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Q7VTF7 (PNCB_BORPE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BP3583
OrganismBordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) [Reference proteome] [HAMAP]
Taxonomic identifier257313 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205820

Sequences

Sequence LengthMass (Da)Tools
Q7VTF7 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 62515B202243589D

FASTA40546,657
        10         20         30         40         50         60 
MVCRNVSRQQ FRAIMIITSL LDTDLYKFSM MQVVLHHFPA AQVEYRYKCR TPGINLRPYL 

        70         80         90        100        110        120 
DEIRAEVHEL CQLRFTSEEL DYLRGLRFIK SDFVDFLGLF HLPERCIFIG EGEQPGEISI 

       130        140        150        160        170        180 
TVKGPWLHTI LFEIPVLAIV NEVYFRNTRR NPDWEEGRKR LQSKMNLVLD DPALADFRVA 

       190        200        210        220        230        240 
EYGTRRRFSK VWHEEIVSTM KARMGVHFAG TSNVLLAMRH GVLPLGTMGH EYLQACQALG 

       250        260        270        280        290        300 
PRLRDSQVFA LEVWAKEYRG DLGIALSDVY GMDAFLRDFD MYFCKLFDGA RHDSGDPFVW 

       310        320        330        340        350        360 
GERLLEHYRT NRADPRAKTL VFSDSLTFPR AIELARQFAG RCKVSFGIGT NLTNDLGHEP 

       370        380        390        400 
LQIVMKMVRC NGQPVAKVSD APEKTMCDDP AYLAYLRQVF QLPPA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640421 Genomic DNA. Translation: CAE43842.1.
RefSeqNP_882096.1. NC_002929.2.

3D structure databases

ProteinModelPortalQ7VTF7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257313.BP3583.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE43842; CAE43842; BP3583.
GeneID2665243.
KEGGbpe:BP3583.
PATRIC21160824. VBIBorPer7866_3877.

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMASIVCKVI.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycBPER257313:BP3583-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BORPE
AccessionPrimary (citable) accession number: Q7VTF7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways