Q7VRU6 (AROC_BLOFL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chorismate synthase
EC=4.2.3.5

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	Bfl500

Organism

Blochmannia floridanus [Complete proteome] [HAMAP]

Taxonomic identifier

203907 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 357	357	Chorismate synthase HAMAP MF_00300		PRO_0000140570

Sequences

	Sequence		Length	Mass (Da)
	Q7VRU6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: B1725E3036D6E5BC	FASTA	357	39,303
	10 20 30 40 50 60 MAGNSIGQYF KVTTFGESHG PAIGGIIDGV PPGLSLNAQD IQFDLNRRRP GTSRYTSPRS 70 80 90 100 110 120 EPDIVEILSG VFNEKTTGTS IGLIIKNIDQ RSQDYEEIKN LYRPGHADYT YEKKYGLRDY 130 140 150 160 170 180 RGGGRSSARE TAIRVAAGAI AKKYLYKINK INIRAYLKQI GHIHCDFKDW IYVNNNPFFC 190 200 210 220 230 240 PNPEQITELD LFIRNLKKLG NSVGAKVTII AENLPIGLGE PVFDRLDADL AHALMSINAV 250 260 270 280 290 300 KGIEIGDGFS AITKLGSEYR DEITSQGFQS NHSGGILGGI STGQPIIMHI AIKPTSSIKI 310 320 330 340 350 PGKTVTNHNQ ETQIITTGRH DPCIGIRIIP IAEAMVAIIL MDHILRFRAQ CGDRKII

References

[1]

"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes." Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed: 12886019] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248583 Genomic DNA. Translation: CAD83189.1.
RefSeq	NP_878783.1. NC_005061.1.
3D structure databases
ProteinModelPortal	Q7VRU6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7VRU6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1499700.
GenomeReviews	Gene locus Bfl500 in contig BX248583_GR.
KEGG	bfl:Bfl500.
PATRIC	31964611. VBICanBlo38691_0488.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0082.
HOGENOM	HBG292336.
OMA	SRFTTQR.
PhylomeDB	Q7VRU6.
ProtClustDB	PRK05382.
Enzyme and pathway databases
BioCyc	CBLO203907:BFL500-MONOMER.
Family and domain databases
HAMAP	MF_00300. Chorismate_synth. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
KO	K01736.
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
SUPFAM	SSF103263. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. AroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BLOFL

Accession

Primary (citable) accession number: Q7VRU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program