Reviewed, UniProtKB/Swiss-Prot Q7VRR0 (RNC_BLOFL)

Names and origin

Protein names

Recommended name:
    Ribonuclease 3
    EC=3.1.26.3
Alternative name(s):
    Ribonuclease III
      Short name=RNase III

Gene names

Name:	rnc
Ordered Locus Names:	Bfl540

Organism

Blochmannia floridanus [Complete proteome] [HAMAP]

Taxonomic identifier

203907 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity.
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. Contains 1 RNase III domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA processing Inferred from electronic annotation. Source: HAMAP rRNA catabolic process Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Ribonuclease 3 HAMAP MF_00104		PRO_0000228503
Regions
	Domain	9 – 131	123	RNase III
	Domain	158 – 228	71	DRBM

Sequences

	Sequence		Length	Mass (Da)
	Q7VRR0-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 2EB2E4757C2275C6	FASTA	232	26,969
	10 20 30 40 50 60 MQCIKCIEIN LLQKKLGYFF HTVDLLLRAL THRSFSNKHN ERLEFLGDSI LNYSITNILY 70 80 90 100 110 120 HRYNHMDEGD MSRIRSSLVC SRTLVELAKE FKLGNCLKLG QGELKNKGYN RESILADTVE 130 140 150 160 170 180 AIIGGIFLDS NIKTIEMLIA FWYQFRLNKI DLEDKQKDPK TRLQEYLQHH HLPLPIYCIN 190 200 210 220 230 QVQGQAHDQI FIMNCQVSSL KYSVMGRGSS RRKAEQDAAE NALKFLIEIN ND

References

[1]

"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes." Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed: 12886019] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX248583 Genomic DNA. Translation: CAD83226.1.
RefSeq	NP_878819.1.
3D structure databases
HSSP	HSSP built from PDB template 1JFZ based on UniProtKB O67082.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7VRR0.
Genome annotation databases
GeneID	1499740.
GenomeReviews	Gene locus Bfl540 in contig BX248583_GR.
KEGG	bfl:Bfl540.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7VRR0.
OMA	ALTHKSF.
Enzyme and pathway databases
BioCyc	CBLO203907:BFL540-MON.
Family and domain databases
HAMAP	MF_00104. [Tree]
InterPro	IPR001159. Ds-RNA_bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNC_BLOFL

Accession

Primary (citable) accession number: Q7VRR0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
Last sequence update:	October 1, 2003
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)