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Q7VRN3 (AROB_BLOFL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:Bfl571
OrganismBlochmannia floridanus [Complete proteome] [HAMAP]
Taxonomic identifier203907 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3643643-dehydroquinate synthase HAMAP MF_00110
PRO_0000140722

Sequences

Sequence LengthMass (Da)Tools
Q7VRN3 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 30C0191A2E09BB75

FASTA36440,644
        10         20         30         40         50         60 
MIKRIIVNVK TGSYPIIIGY GLLNKDFMSY WTIKNGDLVV IITNDRVAPI YLNRLYNSFN 

        70         80         90        100        110        120 
ACEIVTDQCI LPDGEQNKSL SMLNKILTQL LSKNYDRDTI LVALGGGVIG DLTGFAASVY 

       130        140        150        160        170        180 
QRGIRFIQVP TTLLAQVDAS IGGKTGVNHV FGKNMIGSFH QPISVMVDLD CLCTLSEKEF 

       190        200        210        220        230        240 
RSGLSEIIKY AVALDSAFFN WLENNLDYLL MLNPQSLMYC VYRCCELKRS IVIMDEFDQG 

       250        260        270        280        290        300 
IRSVLNLGHT YGHAIESYLG YSQWSHGEAI AAGLMMAVST ALHIGGLISF HDAIRIKLLL 

       310        320        330        340        350        360 
KRANLPICGP EEMKPQDYIK YMIRDKKSRL GRINLVLPKS IGKTQVFVNV NTDVILNAIE 


NIDI

« Hide

References

[1]"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes."
Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A.
Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed: 12886019] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX248583 Genomic DNA. Translation: CAD83253.1.
RefSeqNP_878846.1. NC_005061.1.

3D structure databases

ProteinModelPortalQ7VRN3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7VRN3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1499771.
GenomeReviewsGene locus Bfl571 in contig BX248583_GR.
KEGGbfl:Bfl571.
PATRIC31964761. VBICanBlo38691_0557.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ7VRN3.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycCBLO203907:BFL571-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BLOFL
AccessionPrimary (citable) accession number: Q7VRN3
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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