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Protein

Guanylate kinase

Gene

gmk

Organism
Blochmannia floridanus
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Bfl616
OrganismiBlochmannia floridanus
Taxonomic identifieri203907 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia
Proteomesi
  • UP000002192 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705161 – 210Guanylate kinaseAdd BLAST210

Interactioni

Protein-protein interaction databases

STRINGi203907.Bfl616.

Structurei

3D structure databases

ProteinModelPortaliQ7VRJ7.
SMRiQ7VRJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 186Guanylate kinase-likeUniRule annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037638.
KOiK00942.
OMAiAFIEHAQ.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7VRJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKYSGLLGI ISAPSGAGKS TLINALQKND SILQIKLSIS YTTRKKRPGE
60 70 80 90 100
VHGKDYYFIS IEEFQNMINQ NMFLEYAKVF NHYYGTEKNS IKLMLNSGVH
110 120 130 140 150
VILNIDWQGM NQIRNKKLDF YTIFILPPSQ KELEKRLRFR GLDTDQVIFD
160 170 180 190 200
RMKQAMNEIS HCKEYDYIII NDDFNIALIY LQSVILSKQL KIDYQEYHNS
210
NLINNLLSCL
Length:210
Mass (Da):24,549
Last modified:October 1, 2003 - v1
Checksum:iE06816F15BB4AA1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248583 Genomic DNA. Translation: CAD83291.1.
RefSeqiWP_011126867.1. NC_005061.1.

Genome annotation databases

EnsemblBacteriaiCAD83291; CAD83291; Bfl616.
KEGGibfl:Bfl616.
PATRICi31964853. VBICanBlo38691_0596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248583 Genomic DNA. Translation: CAD83291.1.
RefSeqiWP_011126867.1. NC_005061.1.

3D structure databases

ProteinModelPortaliQ7VRJ7.
SMRiQ7VRJ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203907.Bfl616.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD83291; CAD83291; Bfl616.
KEGGibfl:Bfl616.
PATRICi31964853. VBICanBlo38691_0596.

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037638.
KOiK00942.
OMAiAFIEHAQ.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKGUA_BLOFL
AccessioniPrimary (citable) accession number: Q7VRJ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: October 1, 2003
Last modified: April 12, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.