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Q7VRG3 (PGK_BLOFL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Bfl254
OrganismBlochmannia floridanus [Complete proteome] [HAMAP]
Taxonomic identifier203907 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145923

Regions

Nucleotide binding343 – 3464ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1161Substrate By similarity
Binding site1491Substrate By similarity
Binding site2001ATP By similarity
Binding site3171ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7VRG3 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 2686486100E822EC

FASTA40043,734
        10         20         30         40         50         60 
MVMIKMSDVD LFNKRILIRA DLNVPIRNGI ITSARRIHAS LPTIQLALSR SNQVMVTSHL 

        70         80         90        100        110        120 
GRPVEGEYDS QFSLQPVVDY FQKNLSAKIG GVRLVKDYLD GINWISNELL ILENVRFNKG 

       130        140        150        160        170        180 
EKTDDEVLAK KYASLCDVFV MDAFGSAHRI QSSTHNVSKF VKVACSGLLL EQEIAALHKA 

       190        200        210        220        230        240 
LSNPVRPMVA IVGGSKVSSK LMVLESLSKV VDYLIVGGGI ANTFLAAQGQ NVGKSLYEAE 

       250        260        270        280        290        300 
LISTAKSLLK DCNIPIPTDV RVSSEFSETA QSIMKNVTEI KDDEQILDLG DNSIINILNI 

       310        320        330        340        350        360 
LNNAKTILWN GPVGVFEFPN FRKGTEMVSN AIANSNAFSI AGGGDTLMAI DLFGIANQIS 

       370        380        390        400 
YVSTGGGAFL EFIEGKTLPS IEVLEEHKRM RNGNYSDINY 

« Hide

References

[1]"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes."
Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A.
Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248583 Genomic DNA. Translation: CAD83325.1.
RefSeqNP_878551.1. NC_005061.1.

3D structure databases

ProteinModelPortalQ7VRG3.
SMRQ7VRG3. Positions 3-389.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING203907.Bfl254.

Proteomic databases

PRIDEQ7VRG3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD83325; CAD83325; Bfl254.
GeneID1499454.
KEGGbfl:Bfl254.
PATRIC31964103. VBICanBlo38691_0246.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMADMIFDIG.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycBFLO203907:GHF7-254-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_BLOFL
AccessionPrimary (citable) accession number: Q7VRG3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways