Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q7VRD3

- LPXB_BLOFL

UniProt

Q7VRD3 - LPXB_BLOFL

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Blochmannia floridanus
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciBFLO203907:GHF7-284-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:Bfl284
    OrganismiBlochmannia floridanus
    Taxonomic identifieri203907 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeant endosymbiontsCandidatus Blochmannia
    ProteomesiUP000002192: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 384384Lipid-A-disaccharide synthasePRO_0000190157Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi203907.Bfl284.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7VRD3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018003.
    KOiK00748.
    OMAiVSPITYR.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7VRD3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MINNRSVIIG IVVGENSGDI LGVGLIRSLK KCFKKVQFFG IGGFRMRSEN    50
    MECWYDISEL SIMGITGVIF RLPKLLNMRR ELIKRFLKLK LNIFIGIDFP 100
    DFNISLEKRL KKYGITTIHY VSPSIWAWRS NRVFALKEAT HNVLLLFPFE 150
    KSIYARCGIP NQFIGHPLAD EIPLYPNKIA LRQKFDIPSN RCCLAILPGS 200
    RPKEIQILTK IFMHCAKLLQ DTIPNLEILI PLHDTDLINQ FVTLTSFISV 250
    KFRVLHTLTA WEVMAAADAA LLTSGTATLE CMLAKCPMVV AYRMNPVIFM 300
    LIRHLIKVKW ISLPNLLAGK PIVQEFIQKK CDPQRLASSL FYLLNYNQEQ 350
    RTTLQQEFYH LHRSIKLHAN DQATRLILKY INLL 384
    Length:384
    Mass (Da):44,187
    Last modified:October 1, 2003 - v1
    Checksum:i7FE83D581B23F144
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248583 Genomic DNA. Translation: CAD83355.1.
    RefSeqiNP_878581.1. NC_005061.1.
    WP_011126564.1. NC_005061.1.

    Genome annotation databases

    EnsemblBacteriaiCAD83355; CAD83355; Bfl284.
    GeneIDi1499484.
    KEGGibfl:Bfl284.
    PATRICi31964165. VBICanBlo38691_0277.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248583 Genomic DNA. Translation: CAD83355.1 .
    RefSeqi NP_878581.1. NC_005061.1.
    WP_011126564.1. NC_005061.1.

    3D structure databases

    ProteinModelPortali Q7VRD3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 203907.Bfl284.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAD83355 ; CAD83355 ; Bfl284 .
    GeneIDi 1499484.
    KEGGi bfl:Bfl284.
    PATRICi 31964165. VBICanBlo38691_0277.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018003.
    KOi K00748.
    OMAi VSPITYR.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci BFLO203907:GHF7-284-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiLPXB_BLOFL
    AccessioniPrimary (citable) accession number: Q7VRD3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3