Reviewed, UniProtKB/Swiss-Prot Q7VR41 (AROA_BLOFL)

Names and origin

Protein names

Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferase
    EC=2.5.1.19
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthase
      Short name=EPSP synthase
      Short name=EPSPS

Gene names

Name:	aroA
Ordered Locus Names:	Bfl382

Organism

Blochmannia floridanus [Complete proteome] [HAMAP]

Taxonomic identifier

203907 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the EPSP synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210		PRO_1000012410

Sequences

	Sequence		Length	Mass (Da)
	Q7VR41-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 8B0BC74383411F84	FASTA	433	47,796
	10 20 30 40 50 60 MENFITLNPI KKINGTIYLP GSKSISNRAL LLAAQSVGAT RLINLLDSDD TRYMLAALLQ 70 80 90 100 110 120 LGVKYKLSTD HKICEIKGVG GSLQSKNTQT TLFLGNAGTA IRPLIAALSI KSHNIVLTGD 130 140 150 160 170 180 MRMKERPIFH LVDTLRQGGG RIEYIERDHH LPVKLYGGYC GGNIVIKGDI SSQFLSAVLM 190 200 210 220 230 240 MTPLASKNTY IEVIGSLVSK PYIDITLSVM RAFGICVQHD KDYKFFYCEG NRIYKAPQEY 250 260 270 280 290 300 VIEGDASSAS YFLAAAAIKG GTIRVLGVGK NSKQGDIKFA NILERMGSII TWGDNYIECS 310 320 330 340 350 360 KGIMLKSIDI DVNDIPDAAM TLAVIALFTT NNLPMILRNI YNWRVKESDR LHAMATELRK 370 380 390 400 410 420 VGAIVSEGYD YLHIVPPVQI QSAFINTYND HRIAMCFALV ALSNVSVTIN NPKCVCKTFP 430 DFFDRFLSVG NNL

References

[1]

"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes." Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed: 12886019] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX248583 Genomic DNA. Translation: CAD83448.1.
RefSeq	NP_878673.1.
3D structure databases
HSSP	HSSP built from PDB template 1G6S based on UniProtKB P07638.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7VR41.
Genome annotation databases
GeneID	1499582.
GenomeReviews	Gene locus Bfl382 in contig BX248583_GR.
KEGG	bfl:Bfl382.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7VR41.
OMA	EIDTYND.
Enzyme and pathway databases
BioCyc	CBLO203907:BFL382-MON.
Family and domain databases
HAMAP	MF_00210. [Tree]
InterPro	IPR016228. EPSP_synthase. IPR001986. EPSP_synthase_core. IPR006264. EPSP_synthase_subgroup. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
ProDom	PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01356. aroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROA_BLOFL

Accession

Primary (citable) accession number: Q7VR41

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 1, 2003
Last modified:	November 3, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)