Q7VQQ8 (PLSY_BLOFL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycerol-3-phosphate acyltransferase

Alternative name(s):
Acyl-PO4 G3P acyltransferase
Acyl-phosphate--glycerol-3-phosphate acyltransferase
G3P acyltransferase
Short name=GPAT
EC=2.3.1.n3
Lysophosphatidic acid synthase
Short name=LPA synthase

Gene names

Name:	plsY
Ordered Locus Names:	Bfl060

Organism

Blochmannia floridanus [Complete proteome] [HAMAP]

Taxonomic identifier

203907 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › unclassified Enterobacteriaceae › ant, tsetse, mealybug, aphid, etc. endosymbionts › ant endosymbionts › Candidatus Blochmannia

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO4) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP By similarity. HAMAP-Rule MF_01043
Catalytic activity	Acyl-phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + phosphate. HAMAP-Rule MF_01043
Pathway	Lipid metabolism; phospholipid metabolism. HAMAP-Rule MF_01043
Subunit structure	Probably interacts with PlsX By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01043.
Sequence similarities	Belongs to the PlsY family.

Ontologies

Keywords
Biological process	Lipid biosynthesis Lipid metabolism Phospholipid biosynthesis Phospholipid metabolism
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	acyl-phosphate glycerol-3-phosphate acyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Glycerol-3-phosphate acyltransferase HAMAP-Rule MF_01043		PRO_0000188331
Regions
	Transmembrane	1 – 21	21	Helical; Potential
	Transmembrane	55 – 75	21	Helical; Potential
	Transmembrane	81 – 101	21	Helical; Potential
	Transmembrane	118 – 138	21	Helical; Potential
	Transmembrane	140 – 160	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7VQQ8 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: E160131FD04D426A	FASTA	196	22,711
	10 20 30 40 50 60 MIIFTATLII ILAYFLGSIS GSILICKTLH FKDPRQHGSK NPGTTNILRI INYKIAIFVL 70 80 90 100 110 120 LFDSLKGAVP IWLGTYFHID PIYLYIIAIS ACIGHIYPIY FQFYGGKGVA TAFGALTAIS 130 140 150 160 170 180 INFFIIIIIT WILTVYLFRY ASLGSIVTFI VITFYVWYIQ YHHFEYIILL SLIILSQHKN 190 NIKRLWNHQE KHIWNR

References

[1]

"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes." Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A. Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248583 Genomic DNA. Translation: CAD83585.1.
RefSeq	NP_878372.1. NC_005061.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	203907.Bfl060.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD83585; CAD83585; Bfl060.
GeneID	1499260.
KEGG	bfl:Bfl060.
PATRIC	31963711. VBICanBlo38691_0061.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0344.
HOGENOM	HOG000283806.
KO	K08591.
OMA	WRHRGNL.
ProtClustDB	CLSK2411639.
Enzyme and pathway databases
BioCyc	BFLO203907:GHF7-99-MONOMER.
UniPathway	UPA00085.
Family and domain databases
HAMAP	MF_01043. PlsY.
InterPro	IPR003811. G3P_acylTferase. [Graphical view]
Pfam	PF02660. G3P_acyltransf. 1 hit. [Graphical view]
TIGRFAMs	TIGR00023. TIGR00023. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PLSY_BLOFL

Accession

Primary (citable) accession number: Q7VQQ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program