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Reviewed, UniProtKB/Swiss-Prot Q7VQJ0 (MRAY_BLOFL)

Last modified February 9, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Phospho-N-acetylmuramoyl-pentapeptide-transferase
    EC=2.7.8.13
Alternative name(s):
    UDP-MurNAc-pentapeptide phosphotransferase
Gene names
Name: mraY
Ordered Locus Names: Bfl139
OrganismBlochmannia floridanus [Complete proteome] [HAMAP]
Taxonomic identifier203907 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › ant endosymbionts › Candidatus Blochmannia

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Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP MF_00038

Catalytic activity

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00038

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00038

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_00038.

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP MF_00038
PRO_0000108803

Regions

Transmembrane29 – 4921 Potential
Transmembrane73 – 9321 Potential
Transmembrane97 – 11721 Potential
Transmembrane133 – 15321 Potential
Transmembrane171 – 19121 Potential
Transmembrane202 – 22221 Potential
Transmembrane242 – 26221 Potential
Transmembrane266 – 28621 Potential
Transmembrane291 – 31121 Potential
Transmembrane341 – 36121 Potential

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Sequences

Sequence LengthMass (Da)Tools
Q7VQJ0-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: E7A2EEFC10966B14

FASTA36541,504
        10         20         30         40         50         60 
MLFWIIKITS YFYSSTLFEV MNSVLFRGVG GLFFSLFISI VIGNRIIVWL KYKLRMLQTI 

        70         80         90        100        110        120 
RIDGPQSHKL KYGTPTMGGI IILISVVTSV IIWSDLSNIY IWYILFIFVM YGILGLVDDF 

       130        140        150        160        170        180 
LKIKRGDNLG LTILNKYLWQ SIIAWILIVI MFINRVNYVE NQSGLEFLRN IVCKLKIWDM 

       190        200        210        220        230        240 
ILAYFVIVGT SNSVNLSDGL DGLVIVPVIL VVSGLAIVTW VVGNIYITSD LYIEHVDCIK 

       250        260        270        280        290        300 
ELVVVCASII GAGLGFLWFN SYPSQIFMGD VGSLSLGGVI GLVSILLHQE YLLLIMGGIF 

       310        320        330        340        350        360 
VIESLSVIFQ VSYFKIFKKR IFKMAPIHHH FELKGYMEPK IVVRFWIVSS ILVLLSIVIF 


ILSKY

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References

[1]"The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes."
Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F., Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B., van Ham R.C.H.J., Gross R., Moya A.
Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003) [PubMed: 12886019] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX248583 Genomic DNA. Translation: CAD83660.1.
RefSeqNP_878445.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ7VQJ0.

Genome annotation databases

GeneID1499339.
GenomeReviewsGene locus Bfl139 in contig BX248583_GR.
KEGGbfl:Bfl139.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0472.
HOGENOMHBG708263.
OMAHHHFEQK.
PhylomeDBQ7VQJ0.

Enzyme and pathway databases

BioCycCBLO203907:BFL139-MONOMER.

Family and domain databases

HAMAPMF_00038. MraY.
[Tree]
InterProIPR000715. Glycosyl_transferase_4.
IPR018481. Glycosyl_Trfase_4_cons-reg.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
PANTHERPTHR22926. Glyco_trans_4. 1 hit.
PTHR22926:SF3. PNAcPpept_trans. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00445. mraY. 1 hit.
PROSITEPS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameMRAY_BLOFL
AccessionPrimary (citable) accession number: Q7VQJ0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 1, 2003
Last modified: February 9, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents