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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:HD_0165
OrganismiHaemophilus ducreyi (strain 35000HP / ATCC 700724)
Taxonomic identifieri233412 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000001022 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001287151 – 489Probable malate:quinone oxidoreductaseAdd BLAST489

Interactioni

Protein-protein interaction databases

STRINGi233412.HD0165.

Structurei

3D structure databases

ProteinModelPortaliQ7VPC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7VPC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNHSDSTSYS DITLIGAGIM SATLGTLLAE LVPHKSITIF EQLAEVALES
60 70 80 90 100
SNEWNNAGTG HSALCELNYT EQNAQGEVKI ERAMKICEDF QLSLQLWSYL
110 120 130 140 150
VEQGKIDKPQ EFIHRIPHIS FVQGEDNVAF LRKRYQQLSG HHLFSGMQFS
160 170 180 190 200
RDHAQLAKWM PLIMQNRSAT EILAASYIEN GTDVNFGSLT RKLCAYLTQQ
210 220 230 240 250
GKALKLMHRV KDIKQLANGD WQLTVLDQQQ QQIIHRTKFV FIGCGGGSLP
260 270 280 290 300
LLQKSAIDAG KKIGGFPVSG LFMVCRNPEL VAKHYAKVYG KAKLGAPPMS
310 320 330 340 350
VPHLDTRFID GKQSLLFGPF ASFTLKFLKQ GSVFDLPKSI QASNFSSVMA
360 370 380 390 400
AGIKNLPLAN YLIKQALLTK EQRMVELRDF IPDANSEDWQ VLVAGKRVQV
410 420 430 440 450
LIDGEMRFGT EVVTAEDGSL AVLLGASPGA SISVKAMLDV LLKCFSDELP
460 470 480
AWQHKLQHML PSYQISLRDD AELYATLKRR FEASLLLDQ
Length:489
Mass (Da):54,372
Last modified:October 1, 2003 - v1
Checksum:i47C0510F56F1181D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017143 Genomic DNA. Translation: AAP95158.1.
RefSeqiWP_010944212.1. NC_002940.2.

Genome annotation databases

EnsemblBacteriaiAAP95158; AAP95158; HD_0165.
GeneIDi24943484.
KEGGihdu:HD_0165.

Similar proteinsi

Entry informationi

Entry nameiMQO_HAEDU
AccessioniPrimary (citable) accession number: Q7VPC3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: October 25, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families