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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:HD_0268
OrganismiHaemophilus ducreyi (strain 35000HP / ATCC 700724)
Taxonomic identifieri233412 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000001022 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515631 – 561Arginine--tRNA ligaseAdd BLAST561

Proteomic databases

PRIDEiQ7VP38

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi233412.HD0268

Structurei

3D structure databases

ProteinModelPortaliQ7VP38
SMRiQ7VP38
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi108 – 118"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q7VP38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMIAGAEANV EPLVRQSSKP EFGDYQANGA MAAAKKLAMN PREFAQKILD
60 70 80 90 100
NLDVSDMVDK LEIAGPGFIN IFLKPSWLAK QANFALQAVN FGIKTAQPQT
110 120 130 140 150
ILIDYSSPNV AKEMHVGHLR STIIGDAVVR TLEFLGNNVI RANHVGDWGT
160 170 180 190 200
QFGMLIAYLE KMENEQASEM QLSDLEAFYR AAKESYDSDQ IFAEKARNYV
210 220 230 240 250
VKLQSGDEYC RTMWKKLVDI TMHHNQENYD RLNVTLTEKD VMGESLYNPM
260 270 280 290 300
LPEIVADLKA KGLAVEDNGA VVVFLDEFKN KDGDPMGVII QKSDGGFLYT
310 320 330 340 350
TTDIAAAKYR YETLKVDRAL VFSDSRQAQH MQQAWLITRK AGYVPASFSL
360 370 380 390 400
EHPFFGMMLG KDGKPFKTRS GGTVKLKDLL DEAVERADKL ISARSTNLTV
410 420 430 440 450
AEKSAVVEAV AIGSVKYSDL SKNRTTDYVF DWDNMLTFEG NTAPYMQYAY
460 470 480 490 500
TRIRSIFARA EIDPDTLTGE MQLTEEKERT LALKLLQFEE ALTAVAKEGM
510 520 530 540 550
PHILCQYLYE LAGIFSSFYE ACPMLNADEA IKHSRLRLAS LTAKTLKQGL
560
DLLGIKTVEK M
Length:561
Mass (Da):62,759
Last modified:October 1, 2003 - v1
Checksum:i81FA60A136FFA78D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017143 Genomic DNA Translation: AAP95249.1

Genome annotation databases

EnsemblBacteriaiAAP95249; AAP95249; HD_0268
KEGGihdu:HD_0268

Similar proteinsi

Entry informationi

Entry nameiSYR_HAEDU
AccessioniPrimary (citable) accession number: Q7VP38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: January 31, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome