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Reviewed, UniProtKB/Swiss-Prot Q7VNV1 (ADD_HAEDU)

Last modified February 9, 2010. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase
Gene names
Name: add
Ordered Locus Names: HD_0377
OrganismHaemophilus ducreyi [Complete proteome] [HAMAP]
Taxonomic identifier730 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Sequence similarities

Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine ribonucleoside monophosphate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionadenosine deaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 344344Adenosine deaminase HAMAP MF_00540
PRO_0000194371

Sites

Active site2041 Potential
Active site2511 Potential
Active site2841 Potential
Active site2851 Potential

Sequences

Sequence LengthMass (Da)Tools
Q7VNV1-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 907DA610EBB95A58

FASTA34437,834
        10         20         30         40         50         60 
MVLGLAQYGV IDLHLHLDGS LSPAWMIEWA KKQAVNLPAS TAEALTAYVS VPQDCSDLNE 

        70         80         90        100        110        120 
YLRCFDLPLS LLQTPEALSS AVTDLIQRLD QDGLVYAEIR FAPQLHTQRS MSQEDAVKAA 

       130        140        150        160        170        180 
LRGLQAGLAS TSLFKANLIL CCMRAADNRS ANLETICLAK QYLTKYEAGV VAIDLAGAEG 

       190        200        210        220        230        240 
LFATQHFQQE FDFANQRGVP FTIHAGEAAG PESVQQALDF GATRIGHGIR AIESETVMKQ 

       250        260        270        280        290        300 
LIDKRTPLEM CPCSNLQTKT VAQLADYPLR TFLMRGVVAT LNTDNMTVSQ TCIQQEYRLL 

       310        320        330        340 
AEQYQLSISE AKQLLLNSIA AAFLSNEDKK ALLAHIQQRY PQLI 

« Hide

References

[1]"The complete genome sequence of Haemophilus ducreyi."
Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017143 Genomic DNA. Translation: AAP95347.1.
RefSeqNP_872958.1.

3D structure databases

SMRQ7VNV1. Positions 10-340.
ModBaseSearch...

Genome annotation databases

GeneID1490376.
GenomeReviewsGene locus HD_0377 in contig AE017143_GR.
KEGGhdu:HD0377.
NMPDRfig|233412.1.peg.323.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG630382.
OMAKPGYAEL.

Enzyme and pathway databases

BioCycHDUC233412:HD_0377-MONOMER.
BRENDA3.5.4.4. 265031.

Family and domain databases

HAMAPMF_00540. A_deaminase.
[Tree]
InterProIPR001365. A/AMP_deaminase.
IPR006330. A_deaminase.
[Graphical view]
PANTHERPTHR11409. A/AMP_deaminase. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. aden_deam. 1 hit.
PROSITEPS00485. A_DEAMINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADD_HAEDU
AccessionPrimary (citable) accession number: Q7VNV1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 2, 2004
Last sequence update: October 1, 2003
Last modified: February 9, 2010
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents