Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q7VNR9 (G6PI_HAEDU) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:HD_0418
OrganismHaemophilus ducreyi (strain 35000HP / ATCC 700724) [Complete proteome] [HAMAP]
Taxonomic identifier233412 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length547 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 547547Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180649

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5121 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7VNR9 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 2D28BD06567B5E97

FASTA54761,357
        10         20         30         40         50         60 
MRNINPTDTM AWQALVQHKA EHLSIPQLFA ENEDRFATYN LSFEDQILVD YSKNAINQKT 

        70         80         90        100        110        120 
LTLLRQLAKE CDVDGARQAM FSGEKINRTE NRAVLHIALR NRANKAIFVD GKDVMPAVNA 

       130        140        150        160        170        180 
VLAKMKAFSE KVIKGDWKGY TGKAITDVIN IGIGGSDLGP YMVTEALRPY KNHLNMHFVS 

       190        200        210        220        230        240 
NVDGTHIAEV LRKVNPETTL VLVASKTFTT QETMTNAFSA REWLLADAKD QSAVAKHFVA 

       250        260        270        280        290        300 
LSTNSETVAK FGIDTENMFE FWDWVGGRYS LWSAIGLSIV LSIGFANFEQ LLEGAYAMDK 

       310        320        330        340        350        360 
HFYHTADEQN IPLTLALVSI WNNNFLGAQT EAILPYDQYL HRFAAYFQQG NMESNGKYIG 

       370        380        390        400        410        420 
RDGKAVNYQT GPIIWGEPGT NGQHAFYQLI HQGTTLIPCD FIAPAQTHNP LSDHHNKLLS 

       430        440        450        460        470        480 
NFFAQTEALA FGKSKAQVEL EFTQQGKSLD EVKDIVPFKV FTGNKPTNSI LLKKVTPYSL 

       490        500        510        520        530        540 
GALIAMYEHK IFVQGVLFNI YSFDQWGVEL GKQLANRILP ELEDDQPVVS HDSSTNGLIN 


QFKAWRE 

« Hide

References

[1]"The complete genome sequence of Haemophilus ducreyi."
Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017143 Genomic DNA. Translation: AAP95383.1.
RefSeqNP_872994.1. NC_002940.2.

3D structure databases

ProteinModelPortalQ7VNR9.
SMRQ7VNR9. Positions 17-547.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233412.HD0418.

Proteomic databases

PRIDEQ7VNR9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP95383; AAP95383; HD_0418.
GeneID1490415.
KEGGhdu:HD0418.
PATRIC20177375. VBIHaeDuc133973_0343.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycHDUC233412:GH5F-393-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_HAEDU
AccessionPrimary (citable) accession number: Q7VNR9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways