Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q7VNI8 (NAGZ_HAEDU)

Last modified January 19, 2010. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Beta-hexosaminidase
    EC=3.2.1.52
Alternative name(s):
    N-acetyl-beta-glucosaminidase
    Beta-N-acetylhexosaminidase
Gene names
Name: nagZ
Ordered Locus Names: HD_0542
OrganismHaemophilus ducreyi [Complete proteome] [HAMAP]
Taxonomic identifier730 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides By similarity. HAMAP MF_00364

Catalytic activity

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. HAMAP MF_00364

Pathway

Cell wall biogenesis; peptidoglycan recycling. HAMAP MF_00364

Subcellular location

Cytoplasm By similarity HAMAP MF_00364.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 344344Beta-hexosaminidase HAMAP MF_00364
PRO_0000210788

Sites

Active site2471 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7VNI8-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 14F5BB166A559689

FASTA34438,985
        10         20         30         40         50         60 
MLIIDIKGTE ISQQEIEILS HPLVAGLILF SRNFVDKAQL TALIKEIRQK VTKPLLITID 

        70         80         90        100        110        120 
QEGGRVQRFR EGFTRLPAMQ AFGQLAKHPQ EAIIWAKQAG WLMAAEMFAL DIDLSFAPVL 

       130        140        150        160        170        180 
DLGHKCKAIG DRSFGEKVTQ ILPIAEGFID GMREIGMATT GKHFPGHGQV IADSHLETPF 

       190        200        210        220        230        240 
DERAKANIFN YDIQPFEYFI AKNKLSAIMP AHVVYTQCDP HPASGSTYWL QQVLRQQLQF 

       250        260        270        280        290        300 
KGIIFSDDLG MQGANLMGNF LQRSEQAINA GCDLLLLCNQ PEGVIEVLNG LTYQPNKLEQ 

       310        320        330        340 
QKYLTLKKRR TIDFQQLASS PRYQQTKQHL EQLHECWLEW QTTH 

« Hide

References

[1]"The complete genome sequence of Haemophilus ducreyi."
Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017143 Genomic DNA. Translation: AAP95482.1.
RefSeqNP_873093.1.

3D structure databases

SMRQ7VNI8. Positions 2-337.
ModBaseSearch...

Genome annotation databases

GeneID1490520.
GenomeReviewsGene locus HD_0542 in contig AE017143_GR.
KEGGhdu:HD0542.
NMPDRfig|233412.1.peg.458.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG617255.
OMAVERSIRM.

Enzyme and pathway databases

BioCycHDUC233412:HD_0542-MONOMER.
BRENDA3.2.1.52. 265031.

Family and domain databases

HAMAPMF_00364. NagZ.
[Tree]
InterProIPR019800. Glyco_hydro_3_AS.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glyco_hydro_catalytic_core.
[Graphical view]
Gene3DG3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
PfamPF00933. Glyco_hydro_3. 1 hit.
[Graphical view]
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAGZ_HAEDU
AccessionPrimary (citable) accession number: Q7VNI8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2003
Last modified: January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents