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Protein

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Gene

glpB

Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.UniRule annotation

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FMNUniRule annotation

Pathway:iglycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Anaerobic glycerol-3-phosphate dehydrogenase subunit B (glpB)
This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route), the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciHDUC233412:GH5F-1059-MONOMER.
UniPathwayiUPA00618; UER00673.

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit BUniRule annotation (EC:1.1.5.3UniRule annotation)
Short name:
Anaerobic G-3-P dehydrogenase subunit BUniRule annotation
Short name:
Anaerobic G3Pdhase BUniRule annotation
Gene namesi
Name:glpBUniRule annotation
Ordered Locus Names:HD_1158
OrganismiHaemophilus ducreyi (strain 35000HP / ATCC 700724)
Taxonomic identifieri233412 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000001022 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 426426Anaerobic glycerol-3-phosphate dehydrogenase subunit BPRO_0000204562Add
BLAST

Interactioni

Subunit structurei

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.UniRule annotation

Protein-protein interaction databases

STRINGi233412.HD1158.

Structurei

3D structure databases

ProteinModelPortaliQ7VM49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3075.
KOiK00112.
OMAiDVFEVPM.
OrthoDBiEOG6K6V62.

Family and domain databases

HAMAPiMF_00753. Glycerol3P_GlpB.
InterProiIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsiTIGR03378. glycerol3P_GlpB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7VM49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFDVVIIGG GLAGLTCGIA LQKQGKQCAI INNGQAAIDF SSGSMDLLSC
60 70 80 90 100
LPSGQKVHVF CEAFSELSQQ APEHPYCLLG QHQVVAKVQQ FEQFMQELGL
110 120 130 140 150
VGSHKQNHLR VTPLGGLRHT WLSPKSVPVI AENEHFPYRQ IAILGIEGYH
160 170 180 190 200
DFQPQILVDN LKQNAAFSHC DFSIGYLNIP ELDYLRQNAR EFRSVNIAQL
210 220 230 240 250
LEHKLAFEDL VQEIKQAAGN AQAVFLLACF GLDDQRFFDS LKQATALALF
260 270 280 290 300
ELPTLPPSLI GIRQYRTLRD QFEKLGGLLL NGDRAVRAEF DGDRVARIFT
310 320 330 340 350
TLHQEESINA AHFVLASGSF FSNGLVAEFE RVKEPIFDLD IIGNKAFINS
360 370 380 390 400
ERVSWTDKRF AAAQPYQSAG VAINHHCQVY KNGHLIPNLY AIGNVIGGFW
410 420
GIEQGCASGV SVVTALTVAE WVGGTK
Length:426
Mass (Da):46,953
Last modified:October 1, 2003 - v1
Checksum:i3776BA84EB409CB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017143 Genomic DNA. Translation: AAP96014.1.
RefSeqiWP_010945063.1. NC_002940.2.

Genome annotation databases

EnsemblBacteriaiAAP96014; AAP96014; HD_1158.
KEGGihdu:HD1158.
PATRICi20178653. VBIHaeDuc133973_0964.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017143 Genomic DNA. Translation: AAP96014.1.
RefSeqiWP_010945063.1. NC_002940.2.

3D structure databases

ProteinModelPortaliQ7VM49.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi233412.HD1158.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP96014; AAP96014; HD_1158.
KEGGihdu:HD1158.
PATRICi20178653. VBIHaeDuc133973_0964.

Phylogenomic databases

eggNOGiCOG3075.
KOiK00112.
OMAiDVFEVPM.
OrthoDBiEOG6K6V62.

Enzyme and pathway databases

UniPathwayiUPA00618; UER00673.
BioCyciHDUC233412:GH5F-1059-MONOMER.

Family and domain databases

HAMAPiMF_00753. Glycerol3P_GlpB.
InterProiIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsiTIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of Haemophilus ducreyi."
    Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 35000HP / ATCC 700724.

Entry informationi

Entry nameiGLPB_HAEDU
AccessioniPrimary (citable) accession number: Q7VM49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: July 22, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.