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Q7VM49 (GLPB_HAEDU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3
Gene names
Name:glpB
Ordered Locus Names:HD_1158
OrganismHaemophilus ducreyi (strain 35000HP / ATCC 700724) [Complete proteome] [HAMAP]
Taxonomic identifier233412 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753

Cofactor

FMN By similarity. HAMAP-Rule MF_00753

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753

Subunit structure

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.

Sequence similarities

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
   LigandFlavoprotein
FMN
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 426426Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753
PRO_0000204562

Sequences

Sequence LengthMass (Da)Tools
Q7VM49 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 3776BA84EB409CB3

FASTA42646,953
        10         20         30         40         50         60 
MNFDVVIIGG GLAGLTCGIA LQKQGKQCAI INNGQAAIDF SSGSMDLLSC LPSGQKVHVF 

        70         80         90        100        110        120 
CEAFSELSQQ APEHPYCLLG QHQVVAKVQQ FEQFMQELGL VGSHKQNHLR VTPLGGLRHT 

       130        140        150        160        170        180 
WLSPKSVPVI AENEHFPYRQ IAILGIEGYH DFQPQILVDN LKQNAAFSHC DFSIGYLNIP 

       190        200        210        220        230        240 
ELDYLRQNAR EFRSVNIAQL LEHKLAFEDL VQEIKQAAGN AQAVFLLACF GLDDQRFFDS 

       250        260        270        280        290        300 
LKQATALALF ELPTLPPSLI GIRQYRTLRD QFEKLGGLLL NGDRAVRAEF DGDRVARIFT 

       310        320        330        340        350        360 
TLHQEESINA AHFVLASGSF FSNGLVAEFE RVKEPIFDLD IIGNKAFINS ERVSWTDKRF 

       370        380        390        400        410        420 
AAAQPYQSAG VAINHHCQVY KNGHLIPNLY AIGNVIGGFW GIEQGCASGV SVVTALTVAE 


WVGGTK 

« Hide

References

[1]"The complete genome sequence of Haemophilus ducreyi."
Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017143 Genomic DNA. Translation: AAP96014.1.
RefSeqNP_873625.1. NC_002940.2.

3D structure databases

ProteinModelPortalQ7VM49.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233412.HD1158.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP96014; AAP96014; HD_1158.
GeneID1491081.
KEGGhdu:HD1158.
PATRIC20178653. VBIHaeDuc133973_0964.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3075.
KOK00112.
OMAFRSVNIS.
OrthoDBEOG6K6V62.

Enzyme and pathway databases

BioCycHDUC233412:GH5F-1059-MONOMER.
UniPathwayUPA00618; UER00673.

Family and domain databases

HAMAPMF_00753. Glycerol3P_GlpB.
InterProIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsTIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLPB_HAEDU
AccessionPrimary (citable) accession number: Q7VM49
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways