Q7VL26 (DCD_HAEDU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	HD_1661

Organism

Haemophilus ducreyi (strain 35000HP / ATCC 700724) [Complete proteome] [HAMAP]

Taxonomic identifier

233412 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus ducreyi

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_0000155987

Sequences

	Sequence		Length	Mass (Da)
	Q7VL26 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 72E4EBF982A5B4AD	FASTA	194	21,449
	10 20 30 40 50 60 MRLCDTDIEH YLDQDLINIS PRPTNDKISG ATVDVRLGNS FRVFREHATP YIDLSGPREQ 70 80 90 100 110 120 VSAQLEKIMS DEIILAEGEA FFLHPGELAL ATTLESVKLP DNIVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WHGKIVLEFF NAGKLPLALR PNMAIGALSF EVLSGAAAKP YNAREDAKYK 190 NQQSAISSRI NEDK

References

[1]

"The complete genome sequence of Haemophilus ducreyi." Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017143 Genomic DNA. Translation: AAP96433.1.
RefSeq	NP_874044.1. NC_002940.2.
3D structure databases
ProteinModelPortal	Q7VL26.
SMR	Q7VL26. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	233412.HD1661.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAP96433; AAP96433; HD_1661.
GeneID	1491524.
KEGG	hdu:HD1661.
PATRIC	20179523. VBIHaeDuc133973_1390.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	HDUC233412:GH5F-1448-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR010550. dCTP_deam_bac. [Graphical view]
Pfam	PF06559. DCD. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_HAEDU

Accession

Primary (citable) accession number: Q7VL26

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2004
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program