ID   Q7VIX3_HELHP            Unreviewed;       695 AA.
AC   Q7VIX3;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   RecName: Full=Methyl-accepting chemotaxis protein {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=HH_0481 {ECO:0000313|EMBL:AAP77078.1};
OS   Helicobacter hepaticus (strain ATCC 51449 / 3B1).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=235279 {ECO:0000313|EMBL:AAP77078.1, ECO:0000313|Proteomes:UP000002495};
RN   [1] {ECO:0000313|EMBL:AAP77078.1, ECO:0000313|Proteomes:UP000002495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51449 / 3B1 {ECO:0000313|Proteomes:UP000002495};
RX   PubMed=12810954; DOI=10.1073/pnas.1332093100;
RA   Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M.,
RA   Droege M., Fartmann B., Fischer H.-P., Ge Z., Hoerster A., Holland R.,
RA   Klein K., Koenig J., Macko L., Mendz G.L., Nyakatura G., Schauer D.B.,
RA   Shen Z., Weber J., Frosch M., Fox J.G.;
RT   "The complete genome sequence of the carcinogenic bacterium Helicobacter
RT   hepaticus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7901-7906(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017125; AAP77078.1; -; Genomic_DNA.
DR   RefSeq; WP_011115323.1; NC_004917.1.
DR   AlphaFoldDB; Q7VIX3; -.
DR   STRING; 235279.HH_0481; -.
DR   GeneID; 82178419; -.
DR   KEGG; hhe:HH_0481; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_30_7; -.
DR   Proteomes; UP000002495; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1530; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002495};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          408..457
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          509..683
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          537..560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          606..661
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        537..558
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   695 AA;  76741 MW;  0CB51635F19E8AE4 CRC64;
     MNFFRSLSIG AKIMLGFSSI LVICMLAVTI IIVKISQDIQ MNEANKMLVN AAKREANWVG
     GIFNEIYVAV SASKHFVMRD VQAGAQAILQ NDVMDMFNSN EWGNFGYVYL RDERYKGGNI
     LDSTHKLPNG DFMVLAINEG KNQSRIVPAS EVIANFPSVQ EALSTGKPSV GRPLWVTING
     KEYFGMGINQ PLIDKKGIVQ GVLGVFIDLS TITTILQDPK NSIYKGDFKG VYATDSTIAA
     HGRKEFLGKY LREVNQSPTM NELKHAIENQ IEGIFSYINS LGEMSYTAVA NIHIGDSVDT
     SIWTLIVSAP ESSIYESVSK LRITMIAANI ASIVIVMFVM FIFIRTQIVA RLKNISALLF
     GFFKYIRHEV DIPPAFLTPK ANDEFGIMAK EINQNIQNVQ EGLEQDKKAV EQSIQTAKAI
     EEGDLTARII ENPYNPQLIE LKNVLNTMLD VLQHRVGSNM NEIHRVFESY KTLDFTTEVP
     NAQGSVETTT NILGEEIKKM LRSSSGYAKE LVTQTHQLQE SMNKLLAGNS SQASSLQQSA
     SSIEEISSSM QNVNDKTSEV THQAEDIKNI VGIIRDIADQ TNLLALNAAI EAARAGEHGR
     GFAVVADEVR KLAERTSKSL NEIEANVNVL VQGINEMSES IKEQTLGIEQ INEAIAQLET
     LTDNNVGVAN TTNEIAQNVN QIADDILSDV NKKKF
//