ID   Q7VIU1_HELHP            Unreviewed;       532 AA.
AC   Q7VIU1;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=Methyl-accepting chemotaxis protein {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=HH_0513 {ECO:0000313|EMBL:AAP77110.1};
OS   Helicobacter hepaticus (strain ATCC 51449 / 3B1).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=235279 {ECO:0000313|EMBL:AAP77110.1, ECO:0000313|Proteomes:UP000002495};
RN   [1] {ECO:0000313|EMBL:AAP77110.1, ECO:0000313|Proteomes:UP000002495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51449 / 3B1 {ECO:0000313|Proteomes:UP000002495};
RX   PubMed=12810954; DOI=10.1073/pnas.1332093100;
RA   Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M.,
RA   Droege M., Fartmann B., Fischer H.-P., Ge Z., Hoerster A., Holland R.,
RA   Klein K., Koenig J., Macko L., Mendz G.L., Nyakatura G., Schauer D.B.,
RA   Shen Z., Weber J., Frosch M., Fox J.G.;
RT   "The complete genome sequence of the carcinogenic bacterium Helicobacter
RT   hepaticus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7901-7906(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017125; AAP77110.1; -; Genomic_DNA.
DR   RefSeq; WP_011115355.1; NC_004917.1.
DR   AlphaFoldDB; Q7VIU1; -.
DR   STRING; 235279.HH_0513; -.
DR   GeneID; 82135116; -.
DR   KEGG; hhe:HH_0513; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   OrthoDB; 9776024at2; -.
DR   Proteomes; UP000002495; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 3.30.450.290; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002495};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          200..255
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          260..503
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   532 AA;  59176 MW;  C36FF8C885CA68D6 CRC64;
     MLQSFRSKVL FTLFVFIIIG FSVLYQIVST GYEDMVVKEG KRNAQMLGDS IFQTVRMSMN
     IGVREMIDAG LDNARKIAGV RSLEIHKSQS VIDLFNMPDK VSQKKDIQHI FESKQSQIAE
     VYENGEHNVL LQKPLIADEG CMVCHQDGTL KEGDVLGVLE LRISTESFYE QIEQSENYLL
     LTMFVAGILA LLGLYIFFEK ELVKPLNRLR DMAKDLTEDG GGDLTKRIAI KSNDEVGITS
     NYVNRFIKII QETIAVSKHV SEENTQTCKG LLEMSNVLSK NSDAQFELVD RVNLLAQDVS
     KKLDVAEKTT SSTISDIAQT ESILDDFVKN LQDTIGLITN SAQTQQNILQ HVEELTQHAD
     QIKSVLSIIA DIADQTNLLA LNAAIEAARA GEHGRGFAVV ADEVRKLAEK TQKSLNEIAA
     SVNLVTQSVQ DVGQTIRDTT KDMMYITEKT SPLIDDAHHT QQNLVLTKQN SIHLKDISTS
     IAQSTKELAQ MMQDIVSSSE STQSVGHTIQ KDVNDMSQKA QELDNAITKF KT
//