ID   Q7VGL1_HELHP            Unreviewed;       668 AA.
AC   Q7VGL1;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAP77907.1};
GN   OrderedLocusNames=HH_1310 {ECO:0000313|EMBL:AAP77907.1};
OS   Helicobacter hepaticus (strain ATCC 51449 / 3B1).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=235279 {ECO:0000313|EMBL:AAP77907.1, ECO:0000313|Proteomes:UP000002495};
RN   [1] {ECO:0000313|EMBL:AAP77907.1, ECO:0000313|Proteomes:UP000002495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51449 / 3B1 {ECO:0000313|Proteomes:UP000002495};
RX   PubMed=12810954; DOI=10.1073/pnas.1332093100;
RA   Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M.,
RA   Droege M., Fartmann B., Fischer H.-P., Ge Z., Hoerster A., Holland R.,
RA   Klein K., Koenig J., Macko L., Mendz G.L., Nyakatura G., Schauer D.B.,
RA   Shen Z., Weber J., Frosch M., Fox J.G.;
RT   "The complete genome sequence of the carcinogenic bacterium Helicobacter
RT   hepaticus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7901-7906(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017125; AAP77907.1; -; Genomic_DNA.
DR   RefSeq; WP_011116150.1; NC_004917.1.
DR   AlphaFoldDB; Q7VGL1; -.
DR   STRING; 235279.HH_1310; -.
DR   GeneID; 82135851; -.
DR   KEGG; hhe:HH_1310; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   OrthoDB; 2489132at2; -.
DR   Proteomes; UP000002495; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR013587; Nitrate/nitrite_sensing.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF08376; NIT; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002495};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          338..391
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          410..633
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   668 AA;  75024 MW;  EF17CF1A07AB951E CRC64;
     MTSALRHLSI KIQILALVAI PIIALIYFLF IQFSYTLDSI SQAQNLQKQI HISEQLSRLV
     HEMQKERGMS AGFLASSGTK FANELKGQRL LTDKEHKALS DMLSQSSNLP QSYLTQLHQG
     LESVAKIQQI RNDADKSIED KINIAPQVIG YYTSTIAFLL DSVLESTKII YDAQLAKSMV
     AYTSFLYAKE RAGLERATIN GIFTHNGVPN DNNYNKVVSL IAEQDAYIKF FLSIASQESI
     DFYKNAIKNP SFEQVQQMRE ILHSKRHSGN FGIEPKVWFD TITTKINVLK EVEDFIAHRL
     DSFITQHIQT LQNEFIKWLI LEGVIMIFTL FLCFIVVKNI LTRLNNVNTK LAYITQNKDL
     REQIKVLAND EISAMAHSVN AFIRYIHNVF LEVIKQTKNN LSITQILIDV SHKLDSNTKD
     IAKISENNTG LGEKSYSIIE QNITLSQATK ETLESVLLDV NQTKHIIESI NEEIGQFTIK
     ENQNVEKILS LANEAKNIQS VLIAITDIAD QTNLLALNAA IEAARAGEHG RGFAVVADEV
     RKLAERTQKS ITETSSIIQS ILQSINEISS DMEQSSQSMN HLTQQSEIMH NNIESLSNIV
     QEAMEKSLLN LEGAQKVNAN TSEILDNGIK IASCVAQIVE INEKMQKSSG TLGTQTKTLN
     EMIDTFKI
//