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Q7VEG4

- SPEA_PROMA

UniProt

Q7VEG4 - SPEA_PROMA

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Protein

Biosynthetic arginine decarboxylase

Gene

speA

Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the biosynthesis of agmatine from arginine.UniRule annotation

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

Magnesium.UniRule annotation
Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. arginine catabolic process Source: InterPro
  2. spermidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Polyamine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Magnesium, Metal-binding, Pyridoxal phosphate

Enzyme and pathway databases

BioCyciPMAR167539:GJN2-49-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Biosynthetic arginine decarboxylaseUniRule annotation (EC:4.1.1.19UniRule annotation)
Short name:
ADCUniRule annotation
Gene namesi
Name:speAUniRule annotation
Ordered Locus Names:Pro_0049
OrganismiProchlorococcus marinus (strain SARG / CCMP1375 / SS120)
Taxonomic identifieri167539 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001420: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 648648Biosynthetic arginine decarboxylasePRO_0000149968Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei109 – 1091N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi167539.Pro0049.

Structurei

3D structure databases

ProteinModelPortaliQ7VEG4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni291 – 30111Substrate-bindingUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1166.
KOiK01585.
OMAiIDHYVDG.
OrthoDBiEOG676Z0R.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01417. SpeA.
InterProiIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSiPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR01273. speA. 1 hit.
PROSITEiPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7VEG4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKSKPATKK NEWTVKDSCS LYGLDLWGEE YFSINDSGNV TVSPQGKEGN
60 70 80 90 100
SLELTHLLEE LKGRNLNTPL LLRFDDILED RLKKLHQAFE NAINQYGYNN
110 120 130 140 150
DYQGVFPIKC NQQRHVVEEI VTIGRKWHFG LEAGSKAELL IALALVNDPK
160 170 180 190 200
AFLICNGYKD NRYIETTILA RQLGRQPIVV IEQSDEVGRI IKASQKLGAA
210 220 230 240 250
PLIGIRAKLS NQSSGRWGNS VGEKSKFGLS IPEILKAVQE LTAAGLLNEL
260 270 280 290 300
ILLHFHVGSQ INDIAILKNA LQEASQIYVE LNRLGAPMGH LDVGGGLGVD
310 320 330 340 350
YDGSRTATSA STNYSLQNYA NDVVATIQEC CKAKKVKVPK LISESGRFLS
360 370 380 390 400
SHFSILIFNV LGTSSVPTQI AIETSNECLS VKNLRETLMI LHQICEEKKI
410 420 430 440 450
DVSKLQEAWN DALKFKEDAL NAFRLGFIDL TERATAEQLT WACAKQIAAH
460 470 480 490 500
LPNDLKIPKE LLAINKGLTE TYYANISIFR SAPDTWAIQQ LFPLLPIHRL
510 520 530 540 550
QEKPDQLGHF ADLTCDSDGK LARFINNGQE KFLLELHTVK ANENYWIGMF
560 570 580 590 600
LGGAYQEVMG NLHNLFGSTN AIHIRLTKNG KYKLDHVVRG NSKSDVLQAM
610 620 630 640
EHDSEQLLER IRMASESAIQ QGSLKINDAQ RLIEHVETSL RQSTYLQE
Length:648
Mass (Da):72,378
Last modified:October 1, 2003 - v1
Checksum:i142E509509DFE40A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAP99095.1.
RefSeqiNP_874443.1. NC_005042.1.

Genome annotation databases

EnsemblBacteriaiAAP99095; AAP99095; Pro_0049.
GeneIDi1461427.
KEGGipma:Pro_0049.
PATRICi23026671. VBIProMar8617_0051.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAP99095.1 .
RefSeqi NP_874443.1. NC_005042.1.

3D structure databases

ProteinModelPortali Q7VEG4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167539.Pro0049.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP99095 ; AAP99095 ; Pro_0049 .
GeneIDi 1461427.
KEGGi pma:Pro_0049.
PATRICi 23026671. VBIProMar8617_0051.

Phylogenomic databases

eggNOGi COG1166.
KOi K01585.
OMAi IDHYVDG.
OrthoDBi EOG676Z0R.

Enzyme and pathway databases

BioCyci PMAR167539:GJN2-49-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01417. SpeA.
InterProi IPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSi PR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR01273. speA. 1 hit.
PROSITEi PS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SARG / CCMP1375 / SS120.

Entry informationi

Entry nameiSPEA_PROMA
AccessioniPrimary (citable) accession number: Q7VEG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3