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Q7VEG4

- SPEA_PROMA

UniProt

Q7VEG4 - SPEA_PROMA

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Protein
Biosynthetic arginine decarboxylase
Gene
speA, Pro_0049
Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the biosynthesis of agmatine from arginine By similarity.UniRule annotation

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation
Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. arginine catabolic process Source: InterPro
  2. spermidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Polyamine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Magnesium, Metal-binding, Pyridoxal phosphate

Enzyme and pathway databases

BioCyciPMAR167539:GJN2-49-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Biosynthetic arginine decarboxylase (EC:4.1.1.19)
Short name:
ADC
Gene namesi
Name:speA
Ordered Locus Names:Pro_0049
OrganismiProchlorococcus marinus (strain SARG / CCMP1375 / SS120)
Taxonomic identifieri167539 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001420: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 648648Biosynthetic arginine decarboxylaseUniRule annotation
PRO_0000149968Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei109 – 1091N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Protein-protein interaction databases

STRINGi167539.Pro0049.

Structurei

3D structure databases

ProteinModelPortaliQ7VEG4.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni291 – 30111Substrate-binding Reviewed prediction
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1166.
KOiK01585.
OMAiIDHYVDG.
OrthoDBiEOG676Z0R.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01417. SpeA.
InterProiIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSiPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR01273. speA. 1 hit.
PROSITEiPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7VEG4-1 [UniParc]FASTAAdd to Basket

« Hide

MTKSKPATKK NEWTVKDSCS LYGLDLWGEE YFSINDSGNV TVSPQGKEGN    50
SLELTHLLEE LKGRNLNTPL LLRFDDILED RLKKLHQAFE NAINQYGYNN 100
DYQGVFPIKC NQQRHVVEEI VTIGRKWHFG LEAGSKAELL IALALVNDPK 150
AFLICNGYKD NRYIETTILA RQLGRQPIVV IEQSDEVGRI IKASQKLGAA 200
PLIGIRAKLS NQSSGRWGNS VGEKSKFGLS IPEILKAVQE LTAAGLLNEL 250
ILLHFHVGSQ INDIAILKNA LQEASQIYVE LNRLGAPMGH LDVGGGLGVD 300
YDGSRTATSA STNYSLQNYA NDVVATIQEC CKAKKVKVPK LISESGRFLS 350
SHFSILIFNV LGTSSVPTQI AIETSNECLS VKNLRETLMI LHQICEEKKI 400
DVSKLQEAWN DALKFKEDAL NAFRLGFIDL TERATAEQLT WACAKQIAAH 450
LPNDLKIPKE LLAINKGLTE TYYANISIFR SAPDTWAIQQ LFPLLPIHRL 500
QEKPDQLGHF ADLTCDSDGK LARFINNGQE KFLLELHTVK ANENYWIGMF 550
LGGAYQEVMG NLHNLFGSTN AIHIRLTKNG KYKLDHVVRG NSKSDVLQAM 600
EHDSEQLLER IRMASESAIQ QGSLKINDAQ RLIEHVETSL RQSTYLQE 648
Length:648
Mass (Da):72,378
Last modified:October 1, 2003 - v1
Checksum:i142E509509DFE40A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAP99095.1.
RefSeqiNP_874443.1. NC_005042.1.
WP_011124204.1. NC_005042.1.

Genome annotation databases

EnsemblBacteriaiAAP99095; AAP99095; Pro_0049.
GeneIDi1461427.
KEGGipma:Pro_0049.
PATRICi23026671. VBIProMar8617_0051.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAP99095.1 .
RefSeqi NP_874443.1. NC_005042.1.
WP_011124204.1. NC_005042.1.

3D structure databases

ProteinModelPortali Q7VEG4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167539.Pro0049.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP99095 ; AAP99095 ; Pro_0049 .
GeneIDi 1461427.
KEGGi pma:Pro_0049.
PATRICi 23026671. VBIProMar8617_0051.

Phylogenomic databases

eggNOGi COG1166.
KOi K01585.
OMAi IDHYVDG.
OrthoDBi EOG676Z0R.

Enzyme and pathway databases

BioCyci PMAR167539:GJN2-49-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01417. SpeA.
InterProi IPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSi PR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR01273. speA. 1 hit.
PROSITEi PS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SARG / CCMP1375 / SS120.

Entry informationi

Entry nameiSPEA_PROMA
AccessioniPrimary (citable) accession number: Q7VEG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi