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Q7VE34 (PPNK1_PROMA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 1

Short name=Poly(P)/ATP NAD kinase 1
EC=2.7.1.23
Gene names
Name:ppnK1
Ordered Locus Names:Pro_0180
OrganismProchlorococcus marinus (strain SARG / CCMP1375 / SS120) [Reference proteome] [HAMAP]
Taxonomic identifier167539 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP-Rule MF_00361
PRO_0000229666

Sequences

Sequence LengthMass (Da)Tools
Q7VE34 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 42FF774A5E582438

FASTA30733,863
        10         20         30         40         50         60 
MKLELIWVIY KSGSKSAKEE ALLCSRNIES LGIKVITAES GPLLNTCNNI LNPNKQIPTL 

        70         80         90        100        110        120 
VIVLGGDGTV LGAARHLAMY EVPILSFNVG GNLGFLTHDR QLLKDESLWS RIQEDQFAIE 

       130        140        150        160        170        180 
SRMMLKGRVE SYLDTNDVGK KENFFWALND IYFRSCSEDI SPTCTLELKI DDEDVDIYRG 

       190        200        210        220        230        240 
DGVILSTPTG STAYSMATGG PILHPGIEAI IVSAICPMSL SSRPIVVPAG SRLIIKPVGN 

       250        260        270        280        290        300 
KNQRVNIWQD GVSSALMQKG EQCVIEKARN HAQMLILEQS PSYFRTLTQK LHWAGSLVDN 


QNKMAPK 

« Hide

References

[1]"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome."
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. expand/collapse author list , Wincker P., Wolf Y.I., Hess W.R.
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017126 Genomic DNA. Translation: AAP99226.1.
RefSeqNP_874574.1. NC_005042.1.

3D structure databases

ProteinModelPortalQ7VE34.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING167539.Pro0180.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP99226; AAP99226; Pro_0180.
GeneID1461559.
KEGGpma:Pro_0180.
PATRIC23026947. VBIProMar8617_0187.

Phylogenomic databases

eggNOGCOG0061.
KOK00858.
OMAKLHWAGS.
OrthoDBEOG6PZXDR.
ProtClustDBPRK02645.

Enzyme and pathway databases

BioCycPMAR167539:GJN2-183-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK1_PROMA
AccessionPrimary (citable) accession number: Q7VE34
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families