Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q7VE03 (SYR_PROMA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Pro_0212
OrganismProchlorococcus marinus (strain SARG / CCMP1375 / SS120) [Reference proteome] [HAMAP]
Taxonomic identifier167539 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length603 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 603603Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151589

Regions

Motif143 – 15311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q7VE03 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 47480307399C3839

FASTA60367,957
        10         20         30         40         50         60 
MYNIYKSLNQ QVQRALNTAF PEAASQVKES GDFLNPQLVA ATKPEFGDFQ INGALALARI 

        70         80         90        100        110        120 
IKKSPRQIAE ILIKQLESNE VFKAICLPPE IAGPGFINLT LQNTCLINEI TSRLNDDLLG 

       130        140        150        160        170        180 
VPLVNDDEIT KKLKPVIVDF SSPNIAKEMH VGHLRSTIIG DSIARILNYR GYKVIRLNHV 

       190        200        210        220        230        240 
GDWGTQFGML ITHLKEVAPK ALTTANVINL GNLVEFYKKA KQRFDEDEYF QQCSRNEVVN 

       250        260        270        280        290        300 
LQRGNKESLK AWELLCEQSR KEFNKIYDRL KIEISERGES FYNPFLQGVI DDLTRSGLLV 

       310        320        330        340        350        360 
EDDGAKCVFL NGINGKDGNP LPLIIQKADG GFNYATTDLA AIRYRLKDQP DGDGAGRIIY 

       370        380        390        400        410        420 
VTDSGQANHF AGVFQVAKRA KWLPSSSRIE HVPFGLVQGE DGKKLKTRSG ETVRLKDLLD 

       430        440        450        460        470        480 
EAISRAKLDI ERRLNEENRK ESQAFIEKVS NTIGIAAVKY ADLSQNRITN YQFSFDRMLA 

       490        500        510        520        530        540 
LQGNTAPYLL YAVVRIAGIN RKGGDLHSSV NKLNFSEPQE WRLIRELLKF DEVIIAVEEE 

       550        560        570        580        590        600 
LLPNRLCNYL FELSQVFNRF YDQIPVLKAE EPSRSCRLAL CQLTGDTLKK GLNLLGISTL 


ERM 

« Hide

References

[1]"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome."
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. expand/collapse author list , Wincker P., Wolf Y.I., Hess W.R.
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017126 Genomic DNA. Translation: AAP99258.1.
RefSeqNP_874606.1. NC_005042.1.

3D structure databases

ProteinModelPortalQ7VE03.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING167539.Pro0212.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP99258; AAP99258; Pro_0212.
GeneID1461591.
KEGGpma:Pro_0212.
PATRIC23027011. VBIProMar8617_0219.

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycPMAR167539:GJN2-215-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PROMA
AccessionPrimary (citable) accession number: Q7VE03
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries