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Q7VDZ4

- PGK_PROMA

UniProt

Q7VDZ4 - PGK_PROMA

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401SubstrateUniRule annotation
Binding sitei122 – 1221SubstrateUniRule annotation
Binding sitei155 – 1551SubstrateUniRule annotation
Binding sitei206 – 2061ATPUniRule annotation
Binding sitei297 – 2971ATP; via carbonyl oxygenUniRule annotation
Binding sitei328 – 3281ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi357 – 3604ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR167539:GJN2-224-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Pro_0221
OrganismiProchlorococcus marinus (strain SARG / CCMP1375 / SS120)
Taxonomic identifieri167539 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001420: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 402402Phosphoglycerate kinasePRO_0000145985Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi167539.Pro0221.

Structurei

3D structure databases

ProteinModelPortaliQ7VDZ4.
SMRiQ7VDZ4. Positions 1-401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingUniRule annotation
Regioni63 – 664Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7VDZ4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKRSLSNLS VEDLCGKRVL VRVDFNVPLN EEGSITDDTR IRAALPTIQH
60 70 80 90 100
LIEKEARVIL SAHFGRPKGK VNEDMRLTPV SQRLSELLGK TVVKTESCIG
110 120 130 140 150
PDAEKKVHEM SNGDVVLLEN VRFIGEEEKN DSEFAKKLAS LAEVYVNDAF
160 170 180 190 200
GAAHRAHAST EGVTNYLSPS VAGYLMEKEL KYLQGAIDSP QRPLAAIVGG
210 220 230 240 250
SKVSSKIGVL ESLIDKCDKV LIGGGMIFTF YKARGLSVGK SLVEDDKLDL
260 270 280 290 300
ARALEKKAKE KGVQLLLPSD VVLADNFSPD ASSQMVQIDS IPEGWMGLDI
310 320 330 340 350
GKESVKLFQD ALADCKTVIW NGPMGVFEFD KFANGTNSIS TTLAELSAKG
360 370 380 390 400
CCTIIGGGDS VAAVEKAGLA SKMSHISTGG GASLELLEGK VLPGVAALDD

EI
Length:402
Mass (Da):42,949
Last modified:October 1, 2003 - v1
Checksum:i6EA57B2A697F253D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAP99267.1.
RefSeqiNP_874615.1. NC_005042.1.
WP_011124376.1. NC_005042.1.

Genome annotation databases

EnsemblBacteriaiAAP99267; AAP99267; Pro_0221.
GeneIDi1461600.
KEGGipma:Pro_0221.
PATRICi23027029. VBIProMar8617_0228.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAP99267.1 .
RefSeqi NP_874615.1. NC_005042.1.
WP_011124376.1. NC_005042.1.

3D structure databases

ProteinModelPortali Q7VDZ4.
SMRi Q7VDZ4. Positions 1-401.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167539.Pro0221.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP99267 ; AAP99267 ; Pro_0221 .
GeneIDi 1461600.
KEGGi pma:Pro_0221.
PATRICi 23027029. VBIProMar8617_0228.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci PMAR167539:GJN2-224-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SARG / CCMP1375 / SS120.

Entry informationi

Entry nameiPGK_PROMA
AccessioniPrimary (citable) accession number: Q7VDZ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: October 1, 2003
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3