Q7VDF8 (MQO_PROMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Synonyms:	mqoA
Ordered Locus Names:	Pro_0418

Organism

Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)

Taxonomic identifier

167539 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	496 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 496	496	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128726

Sequences

	Sequence		Length	Mass (Da)
	Q7VDF8 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 33F6F396671CB95B	FASTA	496	54,776
	10 20 30 40 50 60 MVLSDSLASD TRFDAVLIGA GIMSSTLAVL LHELDPEMRI LIVERLEAPA LESSSALNNA 70 80 90 100 110 120 GTGHAANCEF NYTPCHPDGS INIQKALVIN SAFERSLEFW ASMTELGKLS PKTFLNLVPH 130 140 150 160 170 180 ISFVNCEEDV LFLQQRYKKL SAINAFRDME WSADKEELSE WIPLIMNNRN PDQKVAATRV 190 200 210 220 230 240 KRGTDINFGA LTLAYLETLQ ESGAVELKLS TEVVDISRLQ EETWEISLAN TAGTYCVQAP 250 260 270 280 290 300 FLFLGAGGGA LSLLQNSGIE EGKKYGGFPV SGQWLVCNDS KLVKMHHAKV YGKSAIGAPP 310 320 330 340 350 360 MSVPHLDTRW IGTERFLLFG PFAGFNTKFL KNGSNWDFLR SIQFSNFAPM IQTGLRNFDL 370 380 390 400 410 420 IKYLIGQLKL DHDDRIAVLK DFFPEARSSN WTLSLAGQRV QIIKKTSKGG VLKLGTEVVT 430 440 450 460 470 480 SSDGSLAALL GASPGASTAI SIMLEVLQRC WGKKMSTDIW QKRLRDLLPS FGQDINHDKS 490 LLDKLRNRSD SLLGLR

References

[1]

"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome." Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. , Wincker P., Wolf Y.I., Hess W.R. Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017126 Genomic DNA. Translation: AAP99464.1.
RefSeq	NP_874812.1. NC_005042.1.
3D structure databases
ProteinModelPortal	Q7VDF8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1461800.
GenomeReviews	Gene locus Pro_0418 in contig AE017126_GR.
KEGG	pma:Pro0418.
PATRIC	23027453. VBIProMar8617_0427.
Phylogenomic databases
HOGENOM	HBG289663.
OMA	KKWVPLM.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	PMAR167539:PRO_0418-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_PROMA

Accession

Primary (citable) accession number: Q7VDF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program