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Q7VBT3 (AROB_PROMA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:Pro_1009
OrganismProchlorococcus marinus (strain SARG / CCMP1375 / SS120)
Taxonomic identifier167539 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3673673-dehydroquinate synthase HAMAP MF_00110
PRO_0000140765

Sequences

Sequence LengthMass (Da)Tools
Q7VBT3 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: F38FF8A47A17FE07

FASTA36740,728
        10         20         30         40         50         60 
MNQDNCRIKV NLKNNPYEVV VGSEILYTIG EELLRINIRT GEKILIVTNP DVSKPYSRRF 

        70         80         90        100        110        120 
ITSLKEAGYD ANLLILEAGE NKKNYESIAL IHNAAYEHQL DRGSLIIALG GGVIGDMAGF 

       130        140        150        160        170        180 
AAATWLRGID FVQVPTTLLA MVDASVGGKT GVNHPKGKNL IGAFHQPKLV LIDINTLKTL 

       190        200        210        220        230        240 
PQREFRSGMA EIIKYGVIKD LELFNKLENE EDLSNIYSIK ECVLLELIKI SVSIKARIVE 

       250        260        270        280        290        300 
KDEKESGLRA ILNYGHTFGH VIETLCGYGH WLHGEAVSMG MVLIGQLALR KNLWNVDDAL 

       310        320        330        340        350        360 
RQEKLLTKAG LPISWPKINN EDVLRTLKGD KKVDKGNIRL IVPLGIGMVE ILNDVSENEI 


KSLLESI

« Hide

References

[1]"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome."
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. expand/collapse author list , Wincker P., Wolf Y.I., Hess W.R.
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017126 Genomic DNA. Translation: AAQ00054.1.
RefSeqNP_875401.1. NC_005042.1.

3D structure databases

ProteinModelPortalQ7VBT3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1462391.
GenomeReviewsGene locus Pro_1009 in contig AE017126_GR.
KEGGpma:Pro1009.
PATRIC23028739. VBIProMar8617_1060.

Phylogenomic databases

HOGENOMHBG632303.
OMAVMALEMS.

Enzyme and pathway databases

BioCycPMAR167539:PRO_1009-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_PROMA
AccessionPrimary (citable) accession number: Q7VBT3
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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