Q7VBP6 (COMB_PROMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	Pro_1046

Organism

Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)

Taxonomic identifier

167539 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	243 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 243	243	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081470

Sequences

	Sequence		Length	Mass (Da)
	Q7VBP6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: E076FD54F38C7953	FASTA	243	26,435
	10 20 30 40 50 60 MELSYFHVAK DVPSGIKPET SVVIDVLRAT TTIACALNNG AEAVQTFADL DNLKEQASCW 70 80 90 100 110 120 PLSKRLLLGE RGGKKIDGFD LGNSPLAVTS NVVKGKRLFM STTNGTRSLE RVKESKSLYT 130 140 150 160 170 180 MSFINRKAVA EKLISNQSKS VLILGSGWEG AYSLEDSLAA GALASFLLNK NPNSVHILND 190 200 210 220 230 240 ELSAAVALWS CWENNIEGCL RNATHGKRLE RLGNHDDDFT CCSELDKICV VPTQREKGVL CSL

References

[1]

"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome." Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. , Wincker P., Wolf Y.I., Hess W.R. Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017126 Genomic DNA. Translation: AAQ00091.1.
RefSeq	NP_875438.1. NC_005042.1.
3D structure databases
ProteinModelPortal	Q7VBP6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1462428.
GenomeReviews	Gene locus Pro_1046 in contig AE017126_GR.
KEGG	pma:Pro1046.
PATRIC	23028811. VBIProMar8617_1096.
Phylogenomic databases
HOGENOM	HBG633644.
OMA	GWEGAYS.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	PMAR167539:PRO_1046-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_PROMA

Accession

Primary (citable) accession number: Q7VBP6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 2, 2004
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program