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Q7VAW0 (PPNK2_PROMA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2
Short name=Poly(P)/ATP NAD kinase 2
EC=2.7.1.23
Gene names
Name:ppnK2
Ordered Locus Names:Pro_1343
OrganismProchlorococcus marinus (strain SARG / CCMP1375 / SS120)
Taxonomic identifier167539 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361

Subcellular location

Cytoplasm By similarity HAMAP MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361
PRO_0000229667

Sequences

Sequence LengthMass (Da)Tools
Q7VAW0 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 4A319B1CA956C5F6

FASTA30232,889
        10         20         30         40         50         60 
MPRLGLILND GKELALKAAL SIESKLEKSG YEVVRVSSSG GMVGFANPDQ HMRTLGYNAC 

        70         80         90        100        110        120 
VPEGFDPSMK LAIVLGGDGT VLSAARQTAP VGVPILTINT GHLGFLSEAY LPDIDKALEQ 

       130        140        150        160        170        180 
VLASQWEIEE RTSLVVSVMR GEQRRWEALC LNEMALHREP LTSMCHFEIS IGRHAPVDIS 

       190        200        210        220        230        240 
ADGVILSTPT GSTAYSLSAG GPVITPDCPV LQLTPIAPHS LASRALVFSD LEPVTVFPAT 

       250        260        270        280        290        300 
PERLMMVVDG TAGCYVWPED RVLIRKSNHP VRFIRLTDHE FFQVLRKKLG WGLPHVAKPE 


KY

« Hide

References

[1]"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome."
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. expand/collapse author list , Wincker P., Wolf Y.I., Hess W.R.
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017126 Genomic DNA. Translation: AAQ00387.1.
RefSeqNP_875734.1. NC_005042.1.

3D structure databases

ProteinModelPortalQ7VAW0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1462724.
GenomeReviewsGene locus Pro_1343 in contig AE017126_GR.
KEGGpma:Pro1343.
PATRIC23029443. VBIProMar8617_1408.

Phylogenomic databases

HOGENOMHBG713904.
OMAKLGWGLP.
ProtClustDBPRK02649.

Enzyme and pathway databases

BioCycPMAR167539:PRO_1343-MONOMER.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KOK00858.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK2_PROMA
AccessionPrimary (citable) accession number: Q7VAW0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 1, 2003
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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