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Q7VAP3 (Q7VAP3_PROMA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401
Gene names
Name:msrA EMBL AAQ00458.1
Synonyms:msrA2 HAMAP MF_01401
Ordered Locus Names:Pro_1414
OrganismProchlorococcus marinus (strain SARG / CCMP1375 / SS120)
Taxonomic identifier167539 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q7VAP3 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: B1D069EA30D9A5F6

FASTA21224,529
        10         20         30         40         50         60 
MFIFKPILRI LYLTIICICL LLFVPQANAL NDSAVFAGGC FWCLEHDFES LKGVLSVESG 

        70         80         90        100        110        120 
YTGGKTIKPT YKNHKGHQEA IKITFDPLEV SFEELLKTYW RNIDPYDGGG QFCDRGDSYR 

       130        140        150        160        170        180 
PVIFYKDNSQ YDLANNSLIN AAEELSASSN NLAVKIERLD EFWEAEDYHQ DFAQRNSVKY 

       190        200        210 
KFYRYSCGRD QRLDEVWGVN AREGIKWLKK MP

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References

[1]"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome."
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. expand/collapse author list , Wincker P., Wolf Y.I., Hess W.R.
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017126 Genomic DNA. Translation: AAQ00458.1.
RefSeqNP_875805.1. NC_005042.1.

3D structure databases

HSSPHSSP built from PDB template 1FF3 based on UniProtKB P27110.
ProteinModelPortalQ7VAP3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1462796.
GenomeReviewsGene locus Pro_1414 in contig AE017126_GR.
KEGGpma:Pro1414.
PATRIC23029595. VBIProMar8617_1480.

Phylogenomic databases

HOGENOMHBG748152.
OMAHKGHQEA.
ProtClustDBCLSK919692.

Enzyme and pathway databases

BioCycPMAR167539:PRO_1414-MONOMER.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ7VAP3_PROMA
AccessionPrimary (citable) accession number: Q7VAP3
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info