Q7V9U4 (CAPP_PROMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	Pro_1730

Organism

Prochlorococcus marinus (strain SARG / CCMP1375 / SS120) [Reference proteome] [HAMAP]

Taxonomic identifier

167539 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Prochlorales › Prochlorococcaceae › Prochlorococcus › Prochlorococcus marinus › Prochlorococcus marinus subsp. marinus

Protein attributes

Sequence length	1001 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation
Ligand	Magnesium
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1001	1001	Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595		PRO_0000166610
Sites
	Active site	189	1	By similarity
	Active site	642	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7V9U4 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: DAC040EF9398B80E	FASTA	1,001	115,162
	10 20 30 40 50 60 MTELDNFSML EASKQVPDRK ESSQILADHM SGRLLQKRLE LVEDLWETVV RSECPLEQVE 70 80 90 100 110 120 RLLRLKQLSN SSGIVGEEQT NQINEIVELI KEMDLAEAIS AARAFSLYFQ LVNILEQRIE 130 140 150 160 170 180 EDSYLESISR GQEEKINTSI DPFAPPLASQ TAPATFSELF DRLRRLNVPP GQLEELLREM 190 200 210 220 230 240 DIRLVFTAHP TEIVRHTVRH KQRRVASLLQ QLQSDEVFSL SERDNLRLQL EEEIRLWWRT 250 260 270 280 290 300 DELHQFKPTV LDEVDYALHY FQQVLFDAMP QLRRRICSAL SQSYPDIDVP QEAFCTFGSW 310 320 330 340 350 360 VGSDRDGNPS VTPEITWRTA CYQRKLMLDR YMHSVQELRN QLSISMQWSQ VSTQLLESLE 370 380 390 400 410 420 MDRVRFPHIY EERAARYRLE PYRLKLSYTL ERLKFTQQRN QELSEAGWAT TIERTNVSNN 430 440 450 460 470 480 PDEDLHYCSI DEFRRDLELI RNSLVATNLS CEQLDTLLTQ VHIFAFSLAS LDIRQESTRH 490 500 510 520 530 540 SEAIDELTRY LNLPKSYIEM TEDEKVIWLM DELQTLRPLI PSAVQWSKST EETFAVFRML 550 560 570 580 590 600 DRLQKEFGSR ICRSYVISMS HTVSDLLEVL LLAKEYGLVD ISSESSDLLV IPLFETVEDL 610 620 630 640 650 660 QHAPSVMEEL FQSEIYLKLL PRVGEKSQPL QELMLGYSDS NKDSGFLSSN WEIHQAQIAL 670 680 690 700 710 720 QNLASSHGVA LRLFHGRGGS VGRGGGPAYQ AILAQPSGTL KGRIKITEQG EVLASKYSLP 730 740 750 760 770 780 ELALYNLETV TTAVLQNSLV TNQWDATPSW NELMTRLAVR SRQHYRALVH DNPDLVAFFQ 790 800 810 820 830 840 EVTPIEEISK LQISSRPARR KTGAKDLSSL RAIPWVFGWT QSRFLLPSWF GVGTALEEEL 850 860 870 880 890 900 KSDPDHIELL RMLNQRWPFF RMLISKVEMT LSKVDLEVAY HYMTSLGSHE NREAFNCIFE 910 920 930 940 950 960 IISNEYKLTR RLVLEITGKP KLLSADPALQ LSVDLRNRTI VPLGFLQVAL LCRLRDQNRQ 970 980 990 1000 PPMSETLLTE GDIGRTYSRS ELLRGALLTI NGIAAGMRNT G

References

[1]

"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome." Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. , Wincker P., Wolf Y.I., Hess W.R. Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017126 Genomic DNA. Translation: AAQ00774.1.
RefSeq	NP_876121.1. NC_005042.1.
3D structure databases
ProteinModelPortal	Q7V9U4.
ModBase	Search...
Protein-protein interaction databases
STRING	167539.Pro1730.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAQ00774; AAQ00774; Pro_1730.
GeneID	1463112.
KEGG	pma:Pro1730.
PATRIC	23030295. VBIProMar8617_1825.
Phylogenomic databases
eggNOG	COG2352.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Enzyme and pathway databases
BioCyc	PMAR167539:GJN2-1770-MONOMER.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_PROMA

Accession

Primary (citable) accession number: Q7V9U4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program