Reviewed, UniProtKB/Swiss-Prot Q7V9T7 (HEM6_PROMA)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen 3 oxidase, aerobic
    EC=1.3.3.3
Alternative name(s):
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase

Gene names

Name:	hemF
Ordered Locus Names:	Pro_1737

Organism

Prochlorococcus marinus [Complete proteome] [HAMAP]

Taxonomic identifier

1219 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Coproporphyrinogen 3 oxidase, aerobic		PRO_0000109907

Sequences

	Sequence		Length	Mass (Da)
	Q7V9T7-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 1808260C6FD0BF4F	FASTA	343	39,570
	10 20 30 40 50 60 MSLSQPSTQS RVKVKSFLTG LQDDICKGLE NIDGEGTFQE ESWERPEGGG GRSRVMREGR 70 80 90 100 110 120 IFEQGGVNFS EVHGEELPPS ILNQRPEAKG HKWFATGTSM VLHPRNPYIP TVHLNYRYFE 130 140 150 160 170 180 AGPVWWFGGG ADLTPYYPYL KDTRHFHKIH QEACDSINPK LHKVFKPWCD EYFFLKHRNE 190 200 210 220 230 240 SRGVGGIFFD YQDGSGKLYK GQNPNGLSSI ASKELGEYKL SWEDLFSLAK ACGNAFLPSY 250 260 270 280 290 300 IPIIEKRHNQ TFSDRERNFQ LYRRGRYVEF NLVWDRGTIF GLQTNGRTES ILMSLPPLAR 310 320 330 340 WEYGFKAPPE SRESLLTDVF TKPQEWFTDE SLEEKCRPHH AVD

References

[1]

"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome." Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. , Wincker P., Wolf Y.I., Hess W.R. Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SARG / CCMP1375 / SS120.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017126 Genomic DNA. Translation: AAQ00781.1.
RefSeq	NP_876128.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1463119.
GenomeReviews	Gene locus Pro_1737 in contig AE017126_GR.
KEGG	pma:Pro1737.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7V9T7.
Enzyme and pathway databases
BioCyc	PMAR167539:PRO_1737-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_PROMA

Accession

Primary (citable) accession number: Q7V9T7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	October 1, 2003
Last modified:	November 4, 2008
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)