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Reviewed, UniProtKB/Swiss-Prot Q7V9T7 (HEM6_PROMA)

Last modified June 16, 2009. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: Pro_1737
OrganismProchlorococcus marinus [Complete proteome] [HAMAP]
Taxonomic identifier1219 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

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Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 343343Coproporphyrinogen-III oxidase, aerobic
PRO_0000109907

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Sequences

Sequence LengthMass (Da)Tools
Q7V9T7-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 1808260C6FD0BF4F

FASTA34339,570
        10         20         30         40         50         60 
MSLSQPSTQS RVKVKSFLTG LQDDICKGLE NIDGEGTFQE ESWERPEGGG GRSRVMREGR 

        70         80         90        100        110        120 
IFEQGGVNFS EVHGEELPPS ILNQRPEAKG HKWFATGTSM VLHPRNPYIP TVHLNYRYFE 

       130        140        150        160        170        180 
AGPVWWFGGG ADLTPYYPYL KDTRHFHKIH QEACDSINPK LHKVFKPWCD EYFFLKHRNE 

       190        200        210        220        230        240 
SRGVGGIFFD YQDGSGKLYK GQNPNGLSSI ASKELGEYKL SWEDLFSLAK ACGNAFLPSY 

       250        260        270        280        290        300 
IPIIEKRHNQ TFSDRERNFQ LYRRGRYVEF NLVWDRGTIF GLQTNGRTES ILMSLPPLAR 

       310        320        330        340 
WEYGFKAPPE SRESLLTDVF TKPQEWFTDE SLEEKCRPHH AVD

« Hide

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References

[1]"Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome."
Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M., Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J., Tandeau de Marsac N., Weissenbach J. expand/collapse author list , Wincker P., Wolf Y.I., Hess W.R.
Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003) [PubMed: 12917486] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SARG / CCMP1375 / SS120.

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Cross-references

Sequence databases

AE017126 Genomic DNA. Translation: AAQ00781.1.
RefSeqNP_876128.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1463119.
GenomeReviewsGene locus Pro_1737 in contig AE017126_GR.
KEGGpma:Pro1737.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ7V9T7.
OMAQ7V9T7. VFKPWCD.

Enzyme and pathway databases

BioCycPMAR167539:PRO_1737-MON.
BRENDA1.3.3.3. 141456.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_PROMA
AccessionPrimary (citable) accession number: Q7V9T7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: October 1, 2003
Last modified: June 16, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents