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Q7V9S5

- Q7V9S5_PROMA

UniProt

Q7V9S5 - Q7V9S5_PROMA

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Protein
Isocitrate dehydrogenase [NADP]
Gene
icd, Pro_1752
Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciPMAR167539:GJN2-1793-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:Pro_1752Imported
OrganismiProchlorococcus marinus (strain SARG / CCMP1375 / SS120)Imported
Taxonomic identifieri167539 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001420: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi167539.Pro1752.

Structurei

3D structure databases

ProteinModelPortaliQ7V9S5.
SMRiQ7V9S5. Positions 6-474.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 2 hits.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7V9S5-1 [UniParc]FASTAAdd to Basket

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MVHYEKLSPP TTGEKIKFNN GLPIVPANPI IPYIRGDGTG VDIWPATQKV    50
IDQAIEKAYG IDRKIEWFKI YAGDEACDLY GTYQYLPKDT IEAIREYGVA 100
IKGPLTTPIG GGIRSLNVAL RQKFDLYSCV RPCRYYQGTP SPHKHPENLD 150
VIVYRENTED IYIGIEWESN DPIGIKLIEH LNNDVIPASP SLKNRIIPQG 200
SGIGIKPVSK DGSQRHIRRA IQHALKLNGN KRHVTLVHKG NIMKFTEGSF 250
RDWGYELATN EFRNECITER ESWILSNLEQ NPRLSIENNA KLIDPGYESL 300
TKEKKDIICN EVQLVINNIH KTHGNNKWKK MVLVDDRIAD SIFQQIQTRP 350
QEYSILATLN LNGDYISDAA AAIVGGLGMA PGANIGDRAA IFEATHGTAP 400
KHAGLDRINP GSVILSGVMM LEYIGWQEAA DLITKGLSQS IYDKQVTYDL 450
ARLMEPPQSP LSCSEFANAV IERF 474
Length:474
Mass (Da):52,989
Last modified:October 1, 2003 - v1
Checksum:i46FAB7F6418A3143
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAQ00796.1.
RefSeqiNP_876143.1. NC_005042.1.
WP_011125901.1. NC_005042.1.

Genome annotation databases

EnsemblBacteriaiAAQ00796; AAQ00796; Pro_1752.
GeneIDi1463134.
KEGGipma:Pro_1752.
PATRICi23030345. VBIProMar8617_1850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017126 Genomic DNA. Translation: AAQ00796.1 .
RefSeqi NP_876143.1. NC_005042.1.
WP_011125901.1. NC_005042.1.

3D structure databases

ProteinModelPortali Q7V9S5.
SMRi Q7V9S5. Positions 6-474.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167539.Pro1752.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAQ00796 ; AAQ00796 ; Pro_1752 .
GeneIDi 1463134.
KEGGi pma:Pro_1752.
PATRICi 23030345. VBIProMar8617_1850.

Phylogenomic databases

KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Enzyme and pathway databases

BioCyci PMAR167539:GJN2-1793-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 2 hits.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SARG / CCMP1375 / SS120.

Entry informationi

Entry nameiQ7V9S5_PROMA
AccessioniPrimary (citable) accession number: Q7V9S5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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