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Q7V9S5

- Q7V9S5_PROMA

UniProt

Q7V9S5 - Q7V9S5_PROMA

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciPMAR167539:GJN2-1793-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:Pro_1752Imported
    OrganismiProchlorococcus marinus (strain SARG / CCMP1375 / SS120)Imported
    Taxonomic identifieri167539 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
    ProteomesiUP000001420: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi167539.Pro1752.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7V9S5.
    SMRiQ7V9S5. Positions 6-474.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 2 hits.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7V9S5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVHYEKLSPP TTGEKIKFNN GLPIVPANPI IPYIRGDGTG VDIWPATQKV    50
    IDQAIEKAYG IDRKIEWFKI YAGDEACDLY GTYQYLPKDT IEAIREYGVA 100
    IKGPLTTPIG GGIRSLNVAL RQKFDLYSCV RPCRYYQGTP SPHKHPENLD 150
    VIVYRENTED IYIGIEWESN DPIGIKLIEH LNNDVIPASP SLKNRIIPQG 200
    SGIGIKPVSK DGSQRHIRRA IQHALKLNGN KRHVTLVHKG NIMKFTEGSF 250
    RDWGYELATN EFRNECITER ESWILSNLEQ NPRLSIENNA KLIDPGYESL 300
    TKEKKDIICN EVQLVINNIH KTHGNNKWKK MVLVDDRIAD SIFQQIQTRP 350
    QEYSILATLN LNGDYISDAA AAIVGGLGMA PGANIGDRAA IFEATHGTAP 400
    KHAGLDRINP GSVILSGVMM LEYIGWQEAA DLITKGLSQS IYDKQVTYDL 450
    ARLMEPPQSP LSCSEFANAV IERF 474
    Length:474
    Mass (Da):52,989
    Last modified:October 1, 2003 - v1
    Checksum:i46FAB7F6418A3143
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017126 Genomic DNA. Translation: AAQ00796.1.
    RefSeqiNP_876143.1. NC_005042.1.
    WP_011125901.1. NC_005042.1.

    Genome annotation databases

    EnsemblBacteriaiAAQ00796; AAQ00796; Pro_1752.
    GeneIDi1463134.
    KEGGipma:Pro_1752.
    PATRICi23030345. VBIProMar8617_1850.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017126 Genomic DNA. Translation: AAQ00796.1 .
    RefSeqi NP_876143.1. NC_005042.1.
    WP_011125901.1. NC_005042.1.

    3D structure databases

    ProteinModelPortali Q7V9S5.
    SMRi Q7V9S5. Positions 6-474.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 167539.Pro1752.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAQ00796 ; AAQ00796 ; Pro_1752 .
    GeneIDi 1463134.
    KEGGi pma:Pro_1752.
    PATRICi 23030345. VBIProMar8617_1850.

    Phylogenomic databases

    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci PMAR167539:GJN2-1793-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 2 hits.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SARG / CCMP1375 / SS120Imported.

    Entry informationi

    Entry nameiQ7V9S5_PROMA
    AccessioniPrimary (citable) accession number: Q7V9S5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3