Q7V8S6 (MQO_PROMM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	PMT_0255

Organism

Prochlorococcus marinus (strain MIT 9313) [Complete proteome] [HAMAP]

Taxonomic identifier

74547 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	496 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 496	496	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128727

Sequences

	Sequence		Length	Mass (Da)
	Q7V8S6 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: D32F3D17FDC408E9	FASTA	496	53,900
	10 20 30 40 50 60 MVVSDVAGSQ SRYDAVLVGA GIMSATLAAL LHELDPELSL LMVERLQAPG LESSAAENNA 70 80 90 100 110 120 GTGHAANCEL NYTPLQPDGS VATAKALAIN TAFERSLEFW ASLTEKGKLL PQQFLHLVPH 130 140 150 160 170 180 ISVVFGDADL AFLHQRFQQL SALPAFASMQ WSTDVAELAE WMPLVMEGRA NAESVAATCI 190 200 210 220 230 240 KRGTDVDFGL LTGAYVKSLQ ASGALELSCG CEVVHLHRLG KHQWNLDLKH SSGSRSVQTP 250 260 270 280 290 300 FVFLGAGGGA LPLLQRSGIP EAAAYAGFPV SGQWLVCSEP GLTARHHAKV YGKAKVGAPP 310 320 330 340 350 360 MSVPHLDSRW IDGCRSLLFG PYAGFSSKFL KQGSRLDLLR SVRRSNFRSM LEVGFKNFDL 370 380 390 400 410 420 VTYLLSELQQ SEKDRFETLK QFLPNAQLND WKLSVAGQRV QIIKRTAEGG RLQMGTEVVS 430 440 450 460 470 480 AQDGSLAALL GASPGASTAV TVMLEVLQRC WSERMASESW QQRLRKLLPS YGHDPNSEPL 490 LLTQMRIRSN KLLNFT

References

[1]

"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9313.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX548175 Genomic DNA. Translation: CAE20430.1.
RefSeq	NP_894088.1. NC_005071.1.
3D structure databases
ProteinModelPortal	Q7V8S6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7V8S6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1728580.
GenomeReviews	Gene locus PMT_0255 in contig BX548175_GR.
KEGG	pmt:PMT0255.
NMPDR	fig|74547.1.peg.255.
PATRIC	23008257. VBIProMar135351_0290.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	NTQFEVS.
PhylomeDB	Q7V8S6.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	PMAR74547:PMT0255-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_PROMM

Accession

Primary (citable) accession number: Q7V8S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	October 1, 2003
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program