Reviewed, UniProtKB/Swiss-Prot Q7V8F6 (COMB_PROMM)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	PMT_0396

Organism

Prochlorococcus marinus (strain MIT 9313) [Complete proteome] [HAMAP]

Taxonomic identifier

74547 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	243 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 243	243	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081471

Sequences

	Sequence		Length	Mass (Da)
	Q7V8F6-1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 5C5B325E39F85C2C	FASTA	243	26,149
	10 20 30 40 50 60 MQLAYFHVAA DVPQGAEPDA AVVIDVLRAT TTIAWALNNG AEAVETFADL DQLRQSAAQW 70 80 90 100 110 120 PESSRLMLGE RGGQRIEGFD LGNSPVAVVP EQVAGKRLFM STTNGTRSLQ RVRGVQRLFT 130 140 150 160 170 180 LALPNRKAVA DHLLMDPPEQ LWIVGSGWEG AYSLEDSLAA GALADLLLDA AADEACVAND 190 200 210 220 230 240 ELTAALALWQ QWKHDPEACL RQASHGQRLI GLGDHDADFR CCAELDRLSV VPVQVKPGVL CAS

References

[1]

"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX548175 Genomic DNA. Translation: CAE20571.1.
RefSeq	NP_894229.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1728347.
GenomeReviews	Gene locus PMT_0396 in contig BX548175_GR.
KEGG	pmt:PMT0396.
NMPDR	fig|74547.1.peg.396.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7V8F6.
OMA	Q7V8F6. ATTTIAW.
Enzyme and pathway databases
BioCyc	PMAR74547:PMT0396-MON.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
TIGRFAMs	TIGR00298. 2-ph_phosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_PROMM

Accession

Primary (citable) accession number: Q7V8F6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 2, 2004
Last sequence update:	October 1, 2003
Last modified:	June 16, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)