Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Prochlorococcus marinus (strain MIT 9313)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei349 – 3491Proton donorUniRule annotation
Active sitei378 – 3781UniRule annotation
Active sitei480 – 4801UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PMT_0714
OrganismiProchlorococcus marinus (strain MIT 9313)
Taxonomic identifieri74547 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001423: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 551551Glucose-6-phosphate isomerasePRO_0000180705Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi74547.PMT0714.

Structurei

3D structure databases

ProteinModelPortaliQ7V7M6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7V7M6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRHFDRGSF RAVSDVHQLM SFPDFSASDA HVQWQRFNNL LWHHNDLGIW
60 70 80 90 100
LDISRMHINA EDFERLGPRF DQAFKAMQAL EQGAIANTDE QRMVGHYWLR
110 120 130 140 150
QPQLAPDQEV CDHIAKEIDL IETFGSNVIN GLIKAPNGKK FTDVLWIGIG
160 170 180 190 200
GSGLGPLLMI RALQNAEQGL RFHFFDNVDP DGMSRVLGNL GDALSTTLVV
210 220 230 240 250
TVSKSGATPE PHLGMEQARQ RLEAMGGHWA GQAVAVTMLN SQLDQLAQKE
260 270 280 290 300
SWLKRFDMFD WVGGRTSITS AVGLLPAALI GCDIRAFLAG AAQMDEATRV
310 320 330 340 350
SDLHSNPASL MAAAWFVAGD GLGRRDMVVL PYRDRLEVFS RYLQQLVMES
360 370 380 390 400
LGKRLDRDGN VVHQGLAVYG NKGSTDQHAY VQQLRDGVDN FFATFIEVLE
410 420 430 440 450
DVENIPAINN EHPGDFLDGF LQGTRAALSQ GGRQSLTISM RRFDPRRLGA
460 470 480 490 500
LVALFERAVG LYGELVNINA YHQPGVESGK KAAAAILNLQ SRVEDLLADG
510 520 530 540 550
VERSAGEIHQ VIGDGSEEAI FWIMRHLTAN KRGYVAEGDW GIPTSLRFSK

G
Length:551
Mass (Da):60,929
Last modified:March 29, 2005 - v2
Checksum:iB569FD6DC1F98AD0
GO

Sequence cautioni

The sequence CAE20889.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX548175 Genomic DNA. Translation: CAE20889.1. Different initiation.
RefSeqiNP_894546.1. NC_005071.1.

Genome annotation databases

EnsemblBacteriaiCAE20889; CAE20889; PMT_0714.
GeneIDi1728183.
KEGGipmt:PMT0714.
PATRICi23009403. VBIProMar135351_0856.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX548175 Genomic DNA. Translation: CAE20889.1. Different initiation.
RefSeqiNP_894546.1. NC_005071.1.

3D structure databases

ProteinModelPortaliQ7V7M6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi74547.PMT0714.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE20889; CAE20889; PMT_0714.
GeneIDi1728183.
KEGGipmt:PMT0714.
PATRICi23009403. VBIProMar135351_0856.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9313.

Entry informationi

Entry nameiG6PI_PROMM
AccessioniPrimary (citable) accession number: Q7V7M6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: January 7, 2015
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.