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Q7V7M6 (G6PI_PROMM) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:PMT_0714
OrganismProchlorococcus marinus (strain MIT 9313) [Complete proteome] [HAMAP]
Taxonomic identifier74547 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Sequence caution

The sequence CAE20889.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180705

Sites

Active site3491Proton donor By similarity
Active site3781 By similarity
Active site4801 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7V7M6 [UniParc].

Last modified March 29, 2005. Version 2.
Checksum: B569FD6DC1F98AD0

FASTA55160,929
        10         20         30         40         50         60 
MSRHFDRGSF RAVSDVHQLM SFPDFSASDA HVQWQRFNNL LWHHNDLGIW LDISRMHINA 

        70         80         90        100        110        120 
EDFERLGPRF DQAFKAMQAL EQGAIANTDE QRMVGHYWLR QPQLAPDQEV CDHIAKEIDL 

       130        140        150        160        170        180 
IETFGSNVIN GLIKAPNGKK FTDVLWIGIG GSGLGPLLMI RALQNAEQGL RFHFFDNVDP 

       190        200        210        220        230        240 
DGMSRVLGNL GDALSTTLVV TVSKSGATPE PHLGMEQARQ RLEAMGGHWA GQAVAVTMLN 

       250        260        270        280        290        300 
SQLDQLAQKE SWLKRFDMFD WVGGRTSITS AVGLLPAALI GCDIRAFLAG AAQMDEATRV 

       310        320        330        340        350        360 
SDLHSNPASL MAAAWFVAGD GLGRRDMVVL PYRDRLEVFS RYLQQLVMES LGKRLDRDGN 

       370        380        390        400        410        420 
VVHQGLAVYG NKGSTDQHAY VQQLRDGVDN FFATFIEVLE DVENIPAINN EHPGDFLDGF 

       430        440        450        460        470        480 
LQGTRAALSQ GGRQSLTISM RRFDPRRLGA LVALFERAVG LYGELVNINA YHQPGVESGK 

       490        500        510        520        530        540 
KAAAAILNLQ SRVEDLLADG VERSAGEIHQ VIGDGSEEAI FWIMRHLTAN KRGYVAEGDW 

       550 
GIPTSLRFSK G 

« Hide

References

[1]"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation."
Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. expand/collapse author list , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W.
Nature 424:1042-1047(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9313.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX548175 Genomic DNA. Translation: CAE20889.1. Different initiation.
RefSeqNP_894546.1. NC_005071.1.

3D structure databases

ProteinModelPortalQ7V7M6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING74547.PMT0714.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE20889; CAE20889; PMT_0714.
GeneID1728183.
KEGGpmt:PMT0714.
PATRIC23009403. VBIProMar135351_0856.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OrthoDBEOG64R61J.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_PROMM
AccessionPrimary (citable) accession number: Q7V7M6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: June 11, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways