Q7V5X3 (Q7V5X3_PROMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-0-acyl N-acetylglucosamine deacetylase EMBL CAE21587.1
EC=3.5.1.- EMBL CAE21587.1

Gene names

Name:	lpxC EMBL CAE21587.1
Ordered Locus Names:	PMT_1412

Organism

Prochlorococcus marinus (strain MIT 9313) [Complete proteome] [HAMAP]

Taxonomic identifier

74547 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL CAE21587.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7V5X3 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 871DB71C90480E64	FASTA	285	30,238
	10 20 30 40 50 60 MAFWPTSYDR AWTLGGAVSR QGIGLHGGEV AEVRLQPSAQ VGFHVSWLDN SDSPVTLGPH 70 80 90 100 110 120 QVRDSQLCTT LELGDRHLGT VEHLLAALAG CGLTHVEIQV GGEEIPLLDG SALGWVEAIA 130 140 150 160 170 180 EVGLTPAATP RADPLVLEHA LVCHRGSSVI TATPAERFNV VGVIDFPQAA IGHQMLAIEL 190 200 210 220 230 240 TPEGFTEQIA PARTFGFREQ VDQLLAAGLI QGGALDNALV CDGDHWLNPP LRFADEPVRH 250 260 270 280 KLLDLIGDLA LVGFPQAQVL VYRGSHGLHN DLANALLAVC PVTVS

References

[1]

"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX548175 Genomic DNA. Translation: CAE21587.1.
RefSeq	NP_895239.1. NC_005071.1.
3D structure databases
ProteinModelPortal	Q7V5X3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7V5X3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1727984.
GenomeReviews	Gene locus PMT_1412 in contig BX548175_GR.
KEGG	pmt:PMT1412.
NMPDR	fig|74547.1.peg.1406.
PATRIC	23011335. VBIProMar135351_1812.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	KAYKSGH.
PhylomeDB	Q7V5X3.
ProtClustDB	PRK13186.
Enzyme and pathway databases
BioCyc	PMAR74547:PMT1412-MONOMER.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7V5X3_PROMM

Accession

Primary (citable) accession number: Q7V5X3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)