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Q7V581

- PUR5_PROMM

UniProt

Q7V581 - PUR5_PROMM

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene
purM, PMT_1691
Organism
Prochlorococcus marinus (strain MIT 9313)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:PMT_1691
OrganismiProchlorococcus marinus (strain MIT 9313)
Taxonomic identifieri74547 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001423: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 345345Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotationPRO_0000148231Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi74547.PMT1691.

Structurei

3D structure databases

ProteinModelPortaliQ7V581.
SMRiQ7V581. Positions 1-334.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7V581-1 [UniParc]FASTAAdd to Basket

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MDYKTAGVDV QAGRAFIERI RSSVEATHRP EVIGGLGGFG GLMRLPAGLN    50
KPLLVAGTDG VGTKLELAQQ HQAHYGVGLD LVGMCVNDVI TSGAEPLFFL 100
DYIATGALSP EAMAQVVEGI AEGCRRSGCA LLGGETAEMP GFYDPGCYDL 150
AGFCVAVVEE DEMIDGRKIK PGDQIIGVAS SGVHSNGFSL VRKVLALTEA 200
NKNTLFGCDN KPLIETLLTP TTLYGQLVKN LLEAKVPLHG MAHITGGGLP 250
ENLPRCCPKD LVTVIDPSSW TRPELFQWLQ DAGQIPEHDL WHTFNLGVGF 300
CLVVAEEVVS DVLQVCNEQA LQAWPIGQVE TASPSTGERL RGLPS 345
Length:345
Mass (Da):36,691
Last modified:October 1, 2003 - v1
Checksum:i8B3E367544A90666
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX548175 Genomic DNA. Translation: CAE21866.1.
RefSeqiNP_895518.1. NC_005071.1.
WP_011131058.1. NC_005071.1.

Genome annotation databases

EnsemblBacteriaiCAE21866; CAE21866; PMT_1691.
GeneIDi1727715.
KEGGipmt:PMT1691.
PATRICi23012107. VBIProMar135351_2188.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX548175 Genomic DNA. Translation: CAE21866.1 .
RefSeqi NP_895518.1. NC_005071.1.
WP_011131058.1. NC_005071.1.

3D structure databases

ProteinModelPortali Q7V581.
SMRi Q7V581. Positions 1-334.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 74547.PMT1691.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE21866 ; CAE21866 ; PMT_1691 .
GeneIDi 1727715.
KEGGi pmt:PMT1691.
PATRICi 23012107. VBIProMar135351_2188.

Phylogenomic databases

eggNOGi COG0150.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9313.

Entry informationi

Entry nameiPUR5_PROMM
AccessioniPrimary (citable) accession number: Q7V581
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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