SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7V4L5

- Q7V4L5_PROMM

UniProt

Q7V4L5 - Q7V4L5_PROMM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Isocitrate dehydrogenase [NADP]

Gene
icd, PMT_1935
Organism
Prochlorococcus marinus (strain MIT 9313)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:PMT_1935Imported
OrganismiProchlorococcus marinus (strain MIT 9313)Imported
Taxonomic identifieri74547 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000001423: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi74547.PMT1935.

Structurei

3D structure databases

ProteinModelPortaliQ7V4L5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0538.
KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 2 hits.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7V4L5-1 [UniParc]FASTAAdd to Basket

« Hide

MAQFEKLSPP SQGTAIRFVN GQPVIPNEPI IPFIRGDGTG VDIWPATQRV    50
LDAAVTKAYQ GVRRIEWFKV YAGDEACDLY GTYQYLPEDT LEAIRTYGVA 100
IKGPLTTPIG GGIRSLNVAL RQIFDLYSCV RPCRYYKGTP SPHKRPQDLD 150
VIVYRENTED IYMGVEWEAD DPVGKTLREH LNTVVIPANG KLGKRQIPEG 200
SGIGIKPVSK HGSQRHIRKA IQHALRLKGD KRHVTLVHKG NIMKFTEGAF 250
RDWGYELATS EFRDVCITER ESWILGNLEN DPQLSIQANA RMIEPGYDSL 300
TPERKASIDA EVHGVLDAIG TSHGNGQWKA MVLVDDRIAD SIFQQIQTRP 350
QEYSILATLN LNGDYISDAA AAMVGGLGMA PGANIGENAA IFEATHGTAP 400
KHAGLDRINP GSVILSGVMM LEFLGWQEAA DLITKGLSAA IANQQVTYDL 450
ARLMDPPVDP VSCSGFSEAV ISHF 474
Length:474
Mass (Da):51,961
Last modified:October 1, 2003 - v1
Checksum:iD6DBD6364F78E897
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX548175 Genomic DNA. Translation: CAE22109.1.
RefSeqiNP_895760.1. NC_005071.1.

Genome annotation databases

EnsemblBacteriaiCAE22109; CAE22109; PMT_1935.
GeneIDi1729181.
KEGGipmt:PMT1935.
PATRICi23012687. VBIProMar135351_2469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX548175 Genomic DNA. Translation: CAE22109.1 .
RefSeqi NP_895760.1. NC_005071.1.

3D structure databases

ProteinModelPortali Q7V4L5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 74547.PMT1935.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE22109 ; CAE22109 ; PMT_1935 .
GeneIDi 1729181.
KEGGi pmt:PMT1935.
PATRICi 23012687. VBIProMar135351_2469.

Phylogenomic databases

eggNOGi COG0538.
KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Family and domain databases

Gene3Di 3.40.718.10. 2 hits.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9313.

Entry informationi

Entry nameiQ7V4L5_PROMM
AccessioniPrimary (citable) accession number: Q7V4L5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi