Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q7V493 (SYR_PROMM) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:PMT_2070
OrganismProchlorococcus marinus (strain MIT 9313) [Complete proteome] [HAMAP]
Taxonomic identifier74547 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length612 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 612612Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151590

Regions

Motif152 – 16211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q7V493 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 5FA5D2C7B2C427A2

FASTA61267,430
        10         20         30         40         50         60 
MQAHFASEFM LSLAHALESQ LRAAIDRAFP EAAASARESG TGLDPQLAPA SKPEFGDFQA 

        70         80         90        100        110        120 
NAALPLAKPL KQPPRQIAAA IVDQLMVDTA FTAICLTPEI AGPGFINLTV RPECLAAEVQ 

       130        140        150        160        170        180 
ARLADARLGV PLVEGDNDGQ QPTPVVVDFS SPNIAKEMHV GHLRSTIIGD SLARVLEFRG 

       190        200        210        220        230        240 
HPVLRLNHVG DWGTQFGMLI THLKQVAPEA LETADAVDLG DLVVFYRQAK QRFDDDEAFQ 

       250        260        270        280        290        300 
TTSREEVVKL QGGDPISLKA WSLLCDQSRR EFQKIYDRLD VRLNERGESF YNAYLESVVE 

       310        320        330        340        350        360 
DLNVSGLLVS DDGAQCVFLE GVTGKDGKPL PVIVQKSDGG FNYATTDLAA MRYRFAAPPQ 

       370        380        390        400        410        420 
GDGARRVIYV TDAGQANHFA GVFQVAQRAG WIPDAGRLQH VPFGLVQGED GKKLKTRAGD 

       430        440        450        460        470        480 
TVRLRELLDE AVERAESDLR RRLQEEGRDE DESFIEQVAT TVGLAAVKYA DLSQNRITNY 

       490        500        510        520        530        540 
QFSFDRMLAL QGNTAPYLLY AVVRIAGIAR KGGDLDVTTA ELQFSETQEW ALVRELLKFD 

       550        560        570        580        590        600 
AVIAEVEEEL LPNRLCTYLF ELSQVFNRFY DQVPVLKAEQ PSRSCRLALC RLTADTLKLG 

       610 
LSLLGIPTLE RM 

« Hide

References

[1]"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation."
Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. expand/collapse author list , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W.
Nature 424:1042-1047(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9313.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX548175 Genomic DNA. Translation: CAE22244.1.
RefSeqNP_895895.1. NC_005071.1.

3D structure databases

ProteinModelPortalQ7V493.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING74547.PMT2070.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE22244; CAE22244; PMT_2070.
GeneID1728247.
KEGGpmt:PMT2070.
PATRIC23012993. VBIProMar135351_2619.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PROMM
AccessionPrimary (citable) accession number: Q7V493
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: October 1, 2003
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries