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Q7V3M9 (SPEA_PROMP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase

Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:PMM0045
OrganismProchlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) [Complete proteome] [HAMAP]
Taxonomic identifier59919 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length648 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 648648Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
PRO_0000149970

Regions

Region291 – 30111Substrate-binding Potential

Amino acid modifications

Modified residue1091N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7V3M9 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: E7878AB68E181CCE

FASTA64873,425
        10         20         30         40         50         60 
MTDFDTKKLN KKWTIEDSIS TYGIDKWGEK YFSINSEGNI SISPDNKSQK KIDLFKLVKE 

        70         80         90        100        110        120 
FKSREINTPL IIRFNDILKD RIAELNNAFS QAIETYDYKN IYKGVFPIKC NQQRNVLEKI 

       130        140        150        160        170        180 
IEYGDRWNFG LEVGSKSELL IGLSILENQK SLLICNGYKD KKYIETAILA RKLGKHPIIV 

       190        200        210        220        230        240 
IEQRDEVKRI IEAVKDLKAT PILGIRSKLS SKSSGRWSKS VGDNSKFGLS IPEIMLTIKE 

       250        260        270        280        290        300 
LKEANLINEM MLLHFHVGSQ ISDISVIKDA LQEASQIFVE LSKLGAPMKY IDVGGGLGID 

       310        320        330        340        350        360 
FDGTKMSSNT STNYSLQNYA NDVIATVKDS CEVNNIQHPI IISESGRAII SHCSVLIFNI 

       370        380        390        400        410        420 
LGTSHVSSQV KVSDQKKQSL IITNLIETLN QIKNLRDKKE DLSEIIELWN DAKKFKEDCL 

       430        440        450        460        470        480 
VAFRLGFICL EERAYAEELT WACAKEIANQ LENNEIIHPD LSEITDTLAS TYYANLSVFK 

       490        500        510        520        530        540 
SIPDTWAINQ VFPIIPIHRH LEEPFCKGHF ADLTCDSDGK LNNFIDNGKI KSLLNLHPPE 

       550        560        570        580        590        600 
KNNDYLIGIF MAGAYQEALG NFHNLFGNTN VIHIDINEDN SYKIKNIIKE NSKSEILELL 

       610        620        630        640 
DYSSDNLVES IRVNTESAIN NKTLTIQEAR KLIDQIETSL RKSSYLSE 

« Hide

References

[1]"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation."
Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. expand/collapse author list , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W.
Nature 424:1042-1047(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCMP1986 / MED4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX548174 Genomic DNA. Translation: CAE18504.1.
RefSeqNP_892166.1. NC_005072.1.

3D structure databases

ProteinModelPortalQ7V3M9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING59919.PMM0045.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE18504; CAE18504; PMM0045.
GeneID1726342.
KEGGpmm:PMM0045.
PATRIC23030720. VBIProMar68066_0046.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
OrthoDBEOG676Z0R.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycPMAR59919:GJMQ-45-MONOMER.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_PROMP
AccessionPrimary (citable) accession number: Q7V3M9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2003
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families