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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-1,6-bisphosphate aldolase (cbbA,cfxA,fbaA,fda)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei323Proton donorUniRule annotation1
Active sitei352UniRule annotation1
Active sitei454UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPMAR59919:TX50_RS04755-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PMM0890
OrganismiProchlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)
Taxonomic identifieri59919 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000001026 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807061 – 526Glucose-6-phosphate isomeraseAdd BLAST526

Proteomic databases

PRIDEiQ7V1I1

Interactioni

Protein-protein interaction databases

STRINGi59919.PMM0890

Structurei

3D structure databases

ProteinModelPortaliQ7V1I1
SMRiQ7V1I1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C89 Bacteria
COG0166 LUCA
HOGENOMiHOG000131425
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 2 hits
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q7V1I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNDFNSWDK YCNYLWFDKQ VNIWLDISKI NFTLDQISSL ENKFKKVFSA
60 70 80 90 100
LKELEAGAIS NIDEKRQVGH YWLRNPSVAP SNLIKDAINN EIRDISEFGE
110 120 130 140 150
KILEGKITNN KNQKFTNVLW IGIGGSGLGP LLITEALQEN SCGLNFSYID
160 170 180 190 200
NIDPFLISEK LDELSDKLAT TLFVVVSKSG GTPEPKIAMN IIKKHVENKN
210 220 230 240 250
LDWNSNAIAI TMKDSQLYKK AQLENWLKIF NLPDWVGGRT SITSSVGLLP
260 270 280 290 300
LALINRDVSE FIKGAAIMDD LTRIPNIKDN PAALLSSAWF FSGDGIGKRD
310 320 330 340 350
MVVLPYRDRL QVFSKYLQQL VMESLGKKFN RKGEIVHQGI SVFGNKGSTD
360 370 380 390 400
QHAYVQQLRD GIDNFFCVFI ELLDTPNSNF YFDSENPKEF LSGFLQGTRS
410 420 430 440 450
ALSNENRQSI TITLDKLSCL TLGALIALFE RAVSFYAELV DINAYDQPGV
460 470 480 490 500
EAGKKAAAEI IDYQKQVTEI FNNGEELSIK EITSLLRNSS AEPIFFIIRQ
510 520
MCFGNDDYLI NGDWSKPSTI RIKKIS
Length:526
Mass (Da):59,307
Last modified:October 1, 2003 - v1
Checksum:iA785CE626C2AD6CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX548174 Genomic DNA Translation: CAE19349.1
RefSeqiWP_011132523.1, NC_005072.1

Genome annotation databases

EnsemblBacteriaiCAE19349; CAE19349; PMM0890
KEGGipmm:PMM0890

Similar proteinsi

Entry informationi

Entry nameiG6PI_PROMP
AccessioniPrimary (citable) accession number: Q7V1I1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: October 1, 2003
Last modified: June 20, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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